RT Journal Article
T1 Pd-Catalyzed Allylic C-H Activation to Seven-Membered N,O-Heterocycles
A1 Velasco Rubio, Álvaro
A1 Varela Carrete, Jesús Ángel
A1 Saá Rodríguez, Carlos
K1 1,4-Benzodiazepinones
K1 1,4-Benzoxazepines
K1 1,4-Oxazepanes
K1 C-H Activation
K1 N,O-Heterocycles
K1 Palladium
AB Pd-catalyzed allylic C-H activation of simple olefins allows an easy entry to seven-membered N,O-heterocycles such as 1,4-benzoxazepines (1,4-BZOs), 1,4-benzodiazepinones (1,4-BZDs) and 1,4-oxazepanes in good to excellent yields. Straightforward derivatizations of the olefinated 1,4-BZO shows the synthetic utility of this methodology.
PB Royal Society of Chemistry
SN 1359-7345
YR 2021
FD 2021
LK http://hdl.handle.net/10347/27041
UL http://hdl.handle.net/10347/27041
LA eng
NO Velasco-Rubio, A., Varela, J. A., Saá, C. (2021). Pd-Catalyzed Allylic C-H Activation to Seven-Membered N,O-Heterocycles. Chem. Commun., 57, 83, 10915-10918.
NO We acknowledge financial support from MINECO (project CTQ2017-87939R and ORFEO-CINQA network RED2018-102387-T), the Xunta de Galicia (project ED431C 2018/04 and Centro singular de investigación de Galicia accreditation 2019-2022, ED431G 2019/03) and the European Union (European Regional Development Fund –  RDF). A.V.-R. thanks Xunta de Galicia for a predoctoral fellowship (ED481A-2018/34, 2018-2021)
DS Minerva
RD 29 abr 2026