RT Journal Article T1 Breast Milk: A Source of Functional Compounds with Potential Application in Nutrition and Therapy A1 Sánchez Fente, Cristina A1 Franco Fente, Luís A1 Regal López, Patricia A1 Lamas Freire, Alexandre A1 Cepeda Sáez, Alberto A1 Fente Sampayo, Cristina Asunción K1 Breast milk K1 Infant formulas K1 Functional compounds K1 Milk fat globule membrane K1 Breastmilk proteins K1 Oligosaccharides K1 Growth factors K1 Milk exosomes K1 Milk microbiome K1 Probiotics AB Breast milk is an unbeatable food that covers all the nutritional requirements of an infant in its different stages of growth up to six months after birth. In addition, breastfeeding benefits both maternal and child health. Increasing knowledge has been acquired regarding the composition of breast milk. Epidemiological studies and epigenetics allow us to understand the possible lifelong effects of breastfeeding. In this review we have compiled some of the components with clear functional activity that are present in human milk and the processes through which they promote infant development and maturation as well as modulate immunity. Milk fat globule membrane, proteins, oligosaccharides, growth factors, milk exosomes, or microorganisms are functional components to use in infant formulas, any other food products, nutritional supplements, nutraceuticals, or even for the development of new clinical therapies. The clinical evaluation of these compounds and their commercial exploitation are limited by the difficulty of isolating and producing them on an adequate scale. In this work we focus on the compounds produced using milk components from other species such as bovine, transgenic cattle capable of expressing components of human breast milk or microbial culture engineering. PB MDPI SN 2072-6643 YR 2021 FD 2021-03-22 LK https://hdl.handle.net/10347/43459 UL https://hdl.handle.net/10347/43459 LA eng NO Sánchez, C.; Franco, L.; Regal, P.; Lamas, A.; Cepeda, A.; Fente, C. Breast Milk: A Source of Functional Compounds with Potential Application in Nutrition and Therapy. Nutrients 2021, 13, 1026. https://doi.org/10.3390/nu13031026 DS Minerva RD 24 abr 2026