RT Journal Article
T1 Electrodecoration and Characterization of Superparamagnetic Iron Oxide Nanoparticles with Bioactive Synergistic Nanocopper: Magnetic Hyperthermia-Induced Ionic Release for Anti-Biofilm Action
A1 Marchianò, Verdiana
A1 Salvador, Maria
A1 Moyano, Amanda
A1 Gutiérrez, Gemma
A1 Matos, María
A1 Yáñez Vilar, Susana
A1 Piñeiro Redondo, Yolanda
A1 Rivas Rey, José
A1 Martínez García, José Carlos
A1 Peddis, Davide
A1 Blanco López, Maria C.
A1 Rivas, Montserrat
A1 Ditaranto, Nicoletta
A1 Cioffi, Nicola
K1 Copper nanoparticle
K1 SPION
K1 Synergistic bioactivity
K1 Hyperthermia
K1 Ion release
AB The urgency for the availability of new antibacterial/disinfectant agents has become a worldwide priority. At the same time, along with the extensive use of other metal nanoparticles (NPs), the investigation of magnetic NPs (MNPs) in antibacterial studies has turned out to be an increasingly attractive research field. In this context, we present the preparation and characterization of superparamagnetic iron oxide NPs, electrodecorated with antimicrobial copper NPs, able to modulate the release of bioactive species not only by the NP’s stabilizer, but also through the application of a suitable magnetic field. Antimicrobial synergistic CuNPs stabilized by benzalkonium chloride have been used in the current study. We demonstrate the successful preparation of Cu@Fe3O4 MNPs composites through morphological and spectroscopic results. Additionally, an extensive magnetic characterization is reported, along with hyperthermia-induced copper ionic release. On the basis of our results, we propose a new generation of antimicrobial magnetic nanomaterials, whose bioactivity can be also tuned by the application of a magnetic field
PB MDPI
YR 2021
FD 2021
LK http://hdl.handle.net/10347/24468
UL http://hdl.handle.net/10347/24468
LA eng
NO Antibiotics 2021, 10(2), 119; https://doi.org/10.3390/antibiotics10020119
NO This work is part of a project that has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant Agreement No. 813439
DS Minerva
RD 29 abr 2026