RT Journal Article
T1 Instability Due to Drug-Induced Vestibulotoxicity
A1 Sánchez Sellero, Inés
A1 Soto Varela, Andrés
K1 Ototoxicity
K1 Vestibulotoxicity
K1 Ototoxic drugs
K1 Dizziness
K1 Cytostatic drugs
AB OBJECTIVE: The therapeutic use of ototoxic drugs is relatively common, particularly in patients with severe diseases. It is likely that disturbances of balance in these patients are underestimated by clinicians. MATERIALS and METHODS: The purpose of this study was to identify drugs involved in the vestibulotoxic origin of instability in a group of 18 patients. RESULTS: Six patients showed both cochlear and vestibular damage, while 12 were affected only by posterior labyrinthine damage. Four groups of drugs were identified: antibiotics (nine patients), cytostatics (four), anti-tuberculosis medicinal products (three), and other drugs (two). Cytostatics were involved in many cases studied, a fact scarcely reported before. CONCLUSION:  It  is  important  to  ensure  an  early  diagnosis  to  prevent  ototoxic  effects  induced  by  drugs.  We  propose  that  patients  receiving  potential ototoxic drugs undergo cochlear and vestibular assessments. Further, we recommend that patients with instability undergo vestibular rehabilitation.
PB AVES
SN 1308-7649
YR 2016
FD 2016
LK http://hdl.handle.net/10347/22400
UL http://hdl.handle.net/10347/22400
LA eng
NO Sánchez Sellero, I. and Soto Varela, A., 2016. Instability Due to Drug-Induced Vestibulotoxicity. The Journal of International Advanced Otology, 12(2), pp.202-207.
DS Minerva
RD 22 abr 2026