RT Dissertation/Thesis
T1 Gold(I)-catalyzed enantioselective addition and cycloaddition reactions
A1 Fernández Casado, Jaime
K1 Catálise organometálica
K1 Complexos de ouro
K1 Catálise dual sinérxica
K1 Síntese de heterociclos
AB This Doctoral Thesis has been focused on the development of new gold(I)-catalyzed enantioselective addition and cycloaddition reactions. In particular, in the first chapter, dedicated to the development of enantioselective addition reactions, we describe the discovery of the first intermolecular reaction involving the synergistic combination of an enamine-mediated organocatalysis and a gold (I) catalyst, providing the products with moderate to good levels of enantioselectivity.In the second chapter, we describe the successful development of an enantioselective gold(I)-catalyzed (2+2+2) cascade cycloaddition between N-allenamides and alkenyl-oximes, constituting one of the very few catalytic and enantioselective methods that allowed to build aza-bridged bicyclic systems from readily available acyclic starting materials.
YR 2018
FD 2018
LK http://hdl.handle.net/10347/19480
UL http://hdl.handle.net/10347/19480
LA eng
DS Minerva
RD 24 abr 2026