RT Journal Article
T1 Bioanalysis During Pregnancy: Recent Advances and Novel Sampling Strategies
A1 Concheiro Guisán, Ana
A1 Concheiro, Marta
AB Consumption of drugs of abuse, tobacco and alcohol throughout pregnancy is a serious public health problem and results in an important economic cost to the health system. Drug and/or metabolites determination in biological matrices from mother and newborn is an objective measure of in utero drug exposure. We reviewed methods published for the determination of in utero drug exposure from 2007 to 2014, with special focus on meconium, placenta, umbilical cord and newborn hair. Accurate bioanalytical procedures are essential to obtain high-quality data to perform interventions and to establish correlations between analytical measures and clinical outcomes. We included a brief overview of clinical implications of in utero drug exposure to better understand the importance of this serious health issue
PB Taylor and Francis
YR 2014
FD 2014-12
LK https://hdl.handle.net/10347/38666
UL https://hdl.handle.net/10347/38666
LA eng
NO Concheiro-Guisan A, Concheiro M. Bioanalysis during pregnancy: recent advances and novel sampling strategies. Bioanalysis. 2014;6(23):3133-53. doi: 10.4155/bio.14.278. PMID: 25529882.
DS Minerva
RD 24 abr 2026