RT Book,_Section
T1 A heteronuclear ZnGd complex as a potential contrast agent for magnetic resonance imaging
A1 Fondo Busto, María Matilde
A1 Corredoira Vázquez, Julio
A1 García Deibe, Ana María
A1 Sanmartín Matalobos, Jesús
A1 Iglesias Rey, Ramón
A1 Taboada Antelo, Pablo
K1 Gadolinium
K1 Zinc
K1 MRI contrast agent
K1 Schiff base
K1 Imidazolidine
AB A new ligand H3L, with internal compartments for allocating 3d metal ions and external donors to bind 4f ions, was synthesized and completely characterized. Reaction of H3L with zinc(II) and gadolin ium(III) salts allows isolating the heteronuclear complex {[ZnGd(HL)(NO3)(OAc)(CH3OH)](NO3)}∙6H2O (1·6H2O). The ability of 1·6H2O to act as a magnetic resonance imaging (MRI) contrast agent was evaluated and this study shows that both the transversal and longitudinal relaxivities are quite high but the T1/T2 ratio of 7.9 indicates that it could have even greater potential as a T2 contrast agent
PB MDPI
SN 978-3-03842-192-4
YR 2016
FD 2016
LK http://hdl.handle.net/10347/25754
UL http://hdl.handle.net/10347/25754
LA eng
NO Fondo, M., Corredoira-Vázquez, J., García-Deibe, A.M., Sanmartín-Matalobos, J., Iglesias, R. & Taboada, P. (2016). A heteronuclear ZnGd complex as a potential contrast agent for magnetic resonance imaging. In J.A. Seijas, M.P. Vázquez Tato & S.K. Lin. (Ed.), Proceedings ECSOC-20: The 20Th International Electronic Conference On Synthetic Organic Chemistry: November 1-30, 2016. MDPI. doi: 10.3390/ecsoc-20-b003
NO The 20th International Electronic Conference on Synthetic Organic Chemistry session Bioorganic, Medicinal and Natural Products
DS Minerva
RD 23 abr 2026