RT Journal Article
T1 Miniaturized matrix solid-phase dispersion for the analysis of ultraviolet filters and other cosmetic ingredients in personal care products
A1 Celeiro Montero, María
A1 Vázquez Ferreiro, Lúa
A1 Lamas Castro, Juan Pablo
A1 Vila González, Marlene María
A1 García Jares, Carmen María
A1 Llompart Vizoso, María del Pilar
K1 UV filters
K1 Matrix solid-phase dispersion
K1 μ-MSPD
K1 Miniaturized extraction technique
K1 GC–MS/MS
K1 Cosmetic analysis
K1 Personal care products
K1 Fragrance allergens
K1 Preservatives
K1 Plasticizers
K1 Synthetic musks
AB A method based on micro-matrix solid-phase dispersion (μ-MSPD) followed by gas-chromatography tandem mass spectrometry (GC–MS/MS) was developed to analyze UV filters in personal care products. It is the first time that MSPD is employed to extract UV filters from cosmetics samples. This technique provides efficient and low-cost extractions, and allows performing extraction and clean-up in one step, which is one of their main advantages. The amount of sample employed was only 0.1 g and the extraction procedure was performed preparing the sample-sorbent column in a glass Pasteur pipette instead of the classic plastic columns in order to avoid plastizicer contamination. Factors affecting the process such as type of sorbent, and amount and type of elution solvent were studied by a factorial design. The method was validated and extended to other families of cosmetic ingredients such as fragrance allergens, preservatives, plasticizers and synthetic musks, including a total of 78 target analytes. Recovery studies in real sample at several concentration levels were also performed. Finally, the green extraction methodology was applied to the analysis of real cosmetic samples of different nature
PB MDPI
YR 2019
FD 2019
LK http://hdl.handle.net/10347/21232
UL http://hdl.handle.net/10347/21232
LA eng
NO Celeiro, M.; Vazquez, L.; Lamas, J.P.; Vila, M.; Garcia-Jares, C.; Llompart, M. Miniaturized Matrix Solid-Phase Dispersion for the Analysis of Ultraviolet Filters and Other Cosmetic Ingredients in Personal Care Products. Separations 2019, 6, 30
NO This research was supported by the project UNST10-1E-491 (Ministry of Science and Innovation, Spain).The authors belong to the Galician Competitive Research Group GPC2017/04 and to the CRETUS StrategicPartnership (ED431 2018/01). All these programs are co-funded by FEDER (EU)
DS Minerva
RD 25 abr 2026