RT Journal Article
T1 Is adenosine deaminase (ADA) activity in saliva and serum a more accurate disease detection tool than traditional redox balance parameters in early-lactating dairy cows?
A1 Castillo Rodríguez, Cristina
A1 Hernández Bermúdez, Joaquín
A1 Sotillo Mesanza, Juan
A1 Muiño Otero, Rodrigo
A1 Benedito Castellote, José Luis
A1 Gutiérrez Montes, Ana María
A1 Arana Sánchez, Rafael
A1 Matas Quintanilla, Marta
A1 Gutiérrez Panizo, Cándido
A1 Gutiérrez Montes, Ana María
K1 ADA
K1 Saliva
K1 Redox balance
K1 Dairy cows
K1 Early lactation
AB Enzyme adenosine deaminase (ADA) is a marker of inflammation in domestic animals, but it is unclear whether it is a reliable marker of oxidative stress, especially in the transition period in dairy cows. This study aims to assess if ADA and redox status measurements in saliva provide the same utility to detect disease condition as that obtained from serum. Sixty-eight multiparous Holstein cows, between 2 and 3 weeks postpartum were selected. Five study groups were established: control (healthy), and cows with ketosis, mastitis, laminitis, and metritis. The parameters measured were ADA activity, total oxidants (TOS), antioxidants (TAC), and OSi ratio.Regarding redox status, no significant differences arise in both saliva and serum being the correlations negative and not significant. In saliva, ADA activity in healthy cows differs from those with pathological processes, having the lowest activities. In serum, ADA activity is similar in the healthy and ketosis cows, showing the lowest activities meanwhile animals with mastitis, laminitis, or metritis have significantly higher activities. In conclusion, the measurement of ADA activities and redox status in saliva does not give consistent results, being preferable to measure them in serum during the transition period
PB Springer
SN 0165-7380
YR 2023
FD 2023
LK http://hdl.handle.net/10347/30379
UL http://hdl.handle.net/10347/30379
LA eng
NO Castillo, C., Hernandez, J., Sotillo, J. et al. Is adenosine deaminase (ADA) activity in saliva and serum a more accurate disease detection tool than traditional redox balance parameters in early-lactating dairy cows?. Vet Res Commun (2023). https://doi.org/10.1007/s11259-023-10069-2
NO Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature
DS Minerva
RD 23 abr 2026