RT Journal Article
T1 Predictors of periapical bone healing associated with teeth having large periapical lesions following nonsurgical root canal treatment or retreatment: A cone beam computed tomography‐based retrospective study
A1 Mosquera Barreiro, Carolina
A1 Ruíz Piñón, Manuel Carlos
A1 Abella Sans, Francesc
A1 Nagendrababu, Venkateshbabu
A1 Vinothkumar, Thilla Sekar
A1 Martín‐González, Jenifer
A1 Martín Biedma, Benjamín
A1 Castelo Baz, Pablo
K1 Cone beam computed tomography
K1 Follow-up
K1 Periapical healing
K1 Root canal treatment
AB AimSeveral factors influence the condition of the periapical tissues associated with root filled teeth. The primary objective of this study was to retrospectively evaluate the extent and speed of bone healing of large periapical lesions associated with nonsurgical root canal treatment or retreatment. The secondary objective was to analyse the relationship between the time to complete healing when analysed using cone beam computed tomography (CBCT) and other possible predictors that affect healing.MethodologySeventy-nine patients were treated during the years 2013–2020 with large periapical lesions of endodontic origin (10–15 mm) as observed on intraoral periapical radiographs (IOPAR) were included. IOPAR and CBCT were available before treatment and during the follow-up (IOPAR every 6 months and CBCT every 12 months). The volume of periapical lesions was calculated by OsiriX Lite software. Variables such as initial volume of the lesion, age, gender, type of treatment or type of root canal filling were compared to identify the differences between healed and unhealed lesions. Pearson's Chi-square test was used for categorical variables, the t-test for age and the Wilcoxon test for initial volume of the lesion. The association between time to healing and the variables was assessed using univariate analysis and multivariate analysis. The Wilcoxon test was used to observe the association of healing time with categorical variables and the correlation index was measured with the quantitative variables.ResultsOf the 79 cases analysed, 60 lesions (76%) were completely healed as verified by CBCT in a mean healing time of 19 months, of which 60% healed fully between 12 and 18 months. Increase in age of patient and larger initial volume of the lesion were associated with a significantly longer healing time (p < .001). Gender, filling material and type of treatment did not have a significant effect on the healing process (p > .05).ConclusionsClinicians should be aware that periapical lesions in older patients and larger areas of bone loss take longer to heal. CBCT monitoring of large periapical lesions is critical and it can help clinicians in the decision-making process.
PB Wiley
SN 0143-2885
YR 2023
FD 2023
LK http://hdl.handle.net/10347/33166
UL http://hdl.handle.net/10347/33166
LA eng
NO International Endodontic Journal, Volume57, Issue1, January 2024, pages 23-36
DS Minerva
RD 23 abr 2026