RT Dissertation/Thesis
T1 Novel supramolecular designs of cyclic peptides that contain γ- or δ-amino acids
A1 Lamas Pérez, Alejandro
K1 Supramolecular Chemistry
K1 Cyclic Peptide Nanotubes
K1 Non-natural Amino Acids
AB Cyclic peptides have the ability to provide supramolecular tubular structures through supramolecular stacking of the peptidic subunits. This self-assembly capability makes them an attractive platform for the construction of complex structures with programmable dimensions. The peptide nature of the resulting systems converts them into suitable candidates for the development of novel nanobiomaterials. In this PhD Thesis, a novel class of cyclic peptides that incorporates cyclic non-natural amino acids are introduced. Their supramolecular properties as well as their ability to encapsulate different hydrophobic substances were explored. Finally, the introduction of a molecular cap was proposed with the aim of obtaining peptide-based molecular containers with improved encapsulation properties.
YR 2022
FD 2022
LK http://hdl.handle.net/10347/28742
UL http://hdl.handle.net/10347/28742
LA eng
DS Minerva
RD 24 abr 2026