RT Journal Article
T1 Association between blood eosinophil count with asthma hospital readmissions
A1 González Barcala, Francisco Javier
A1 San José Capilla, María Esther
A1 Nieto Fontarigo, Juan José
A1 Carreira Villamor, José Martín
A1 Calvo Álvarez, Uxío
A1 Cruz, María Jesús
A1 Facal Mayo, David
A1 García Sanz, María Teresa
A1 Valdés Cuadrado, Luis
A1 Salgado Castro, Francisco Javier
K1 Asthma
K1 Eosinophils
K1 Hospital admissions
K1 Readmissions
K1 Prognosis
K1 Severity
AB Introduction: The presence of eosinophils in asthma inflammation is a relevant factor in the pathophysiology of the disease, however the relationship between the blood eosinophil count (BEC) with asthma severity and prognosis is still under debate.The aim of this work is to analyze the relationship between the BEC levels and hospital readmissions in patients with asthma.Material and methods: A review was retrospectively carried out on all admissions of patients over 18 years old due to exacerbation of asthma occurring in our hospital between the years 2000 and 2010. The personal characteristics and the asthma personal history of each patient were recorded. The BEC was determined from the first blood sample taken from the patient after their arrival at the hospital. Hospital early, late and frequent readmissions were analyzed using 4 cut-off points; less than 150 eosinophils/μL vs ≥150/μL, less than 200 vs 200 /μL, less than 300 vs ≥300/μL, and less than 400 vs ≥400/μL.Results: We have included 1316 patients, 70% of whom are women, as well as a mean age of 60 years, and a mean FEV1 of 73.5% of the reference value. The mean eosinophil blood count was 201.7 cells/μL. A BEC ≥300 cells/μL showed a reduction of risk of late readmission of 42%, a BEC ≥400 cells/μL showed a reduction in late readmission risk of 41% and decrease in frequent late readmission of 63%.Conclusions: Our study appears to support that an elevated BEC is associated with a lower incidence of asthma hospital readmissions.
PB Elsevier
SN 0953-6205
YR 2018
FD 2018
LK http://hdl.handle.net/10347/32551
UL http://hdl.handle.net/10347/32551
LA eng
NO European Journal of Internal Medicine. Volume 53, July 2018, Pages 34-39. https://doi.org/10.1016/j.ejim.2018.02.034
NO This is an Accepted Manuscript of an article published in European Journal of Internal Medicine on 2018, available at: https://doi.org/10.1016/j.ejim.2018.02.034
DS Minerva
RD 23 abr 2026