RT Journal Article T1 Apathy and agitation in institutionalized older adults: an empirically derived classification A1 Mouriz Corbelle, Romina A1 Caamaño Ponte, José A1 Dosil Díaz, Carlos A1 Picón Prado, Eduardo A1 Facal Mayo, David K1 Agitation K1 Apathy K1 Behavioural and psychological symptoms of dementia K1 Cluster analysis K1 Nursing homes AB Background: Apathy and agitation are often recognized as the most problematic behavioural and psychological symptoms in care settings. In this study, we analyze the relationship between apathy and agitation symptoms other and their relationship with demographic, cognitive, and neuropsychiatric variables and psychotropic medication use. Methods: A retrospective study was conducted at a gerontological care centre in Láncara, Spain. Participants were 196 residents of the gerontological care centre, including 143 with a diagnosis of dementia. Apathy and agitation were assessed with the Apathy Scale for Institutionalized Patients with Dementia, Nursing Home version, and the Spanish version of the Cohen-Mansfield Agitation Inventory, respectively. Two-stage hierarchical cluster analysis (hierarchical cluster analysis in a first exploratory stage and K-means clustering to obtain the final solution in the second stage) was conducted to assign residents to different groups based on apathy and agitation scores. Results: In cluster 1, a certain level of apathy, the highest levels of agitation, and the most frequent intake of atypical antipsychotics and clomethiazole were observed. The highest levels of apathy and the most frequent intake of memantine were seen in cluster 2. The lowest levels of agitation and apathy and the highest levels of cognitive performance were found in cluster 3. Conclusions: In this study, subjects with dementia were in a state of high agitation and eventual apathy, had low cognitive status, and were very old. Patients with this profile require well-designed non-pharmacological interventions PB Wiley SN 1346-3500 YR 2021 FD 2021-05 LK https://hdl.handle.net/10347/45958 UL https://hdl.handle.net/10347/45958 LA eng NO Mouriz-Corbelle, R., Caamaño-Ponte, J., Dosil, C., Picón, E., & Facal, D. (2021). Apathy and agitation in institutionalized older adults: an empirically derived classification. Psychogeriatrics, 21(3), 272-278. https://doi.org/10.1111/psyg.12659 NO This is the peer reviewed version of the following article: Mouriz-Corbelle, R., Caamaño-Ponte, J., Dosil, C., Picón, E., & Facal, D. (2021). Apathy and agitation in institutionalized older adults: an empirically derived classification. Psychogeriatrics, 21(3), 272-278, which has been published in final form at: https://doi.org/10.1111/psyg.12659. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited DS Minerva RD 23 abr 2026