RT Journal Article
T1 Single‐Molecule Approach to DNA Minor‐Groove Association Dynamics
A1 Bordello Malde, Jorge
A1 Sánchez López, Mateo Isidro
A1 Vázquez Sentís, Marco Eugenio
A1 Mascareñas Cid, José Luis
A1 Al-Soufi, Wajih
A1 Novo, Mercedes
K1 Binding dynamics
K1 DNA
K1 Fluorescence correlation spectroscopy
K1 Minor-groove binders
K1 Molecular recognition
AB Getting in the groove: Fluorescence correlation spectroscopy reveals that the dynamics of the association process of the bisbenzamidine minor‐groove binder BBA‐OG (blue with green star, see scheme) to dsDNA is not controlled by diffusion, but by the insertion of the binder into the groove at the specific site (red), as shown by the rate constants for each step of the binding event
PB Wiley
SN 1433-7851
YR 2012
FD 2012
LK http://hdl.handle.net/10347/18475
UL http://hdl.handle.net/10347/18475
LA eng
NO Bordello, J. , Sánchez, M. I., Vázquez, M. E., Mascareñas, J. L., Al‐Soufi, W. and Novo, M. (2012), Single‐Molecule Approach to DNA Minor‐Groove Association Dynamics. Angew. Chem. Int. Ed., 51: 7541-7544. doi:10.1002/anie.201201099
NO This is the peer reviewed version of the following article: Bordello, J. , Sánchez, M. I., Vázquez, M. E., Mascareñas, J. L., Al‐Soufi, W. and Novo, M. (2012), Single‐Molecule Approach to DNA Minor‐Groove Association Dynamics. Angew. Chem. Int. Ed., 51: 7541-7544, which has been published in final form at https://doi.org/10.1002/anie.201201099. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions
NO Ministerio de Ciencia e Innovación. Grant Numbers: CTQ2010‐21369, SAF2007‐61015, SAF2010‐20822‐C02, CTQ2009‐14431/BQU, CSD2007‐00006Xunta de Galicia. Grant Numbers: INCITE09262304PR, INCITE09E2R209064ES, IN845B‐2010/094, INCITE09 209 084PR, GRC2010/12, PGIDIT08CSA‐047209PR
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RD 7 jun 2026