RT Book,_Section
T1 Interest of 3-arylcoumarins as xanthine oxidase inhibitors
A1 Matos, Maria João Correia Pinto Carvalho de
A1 Borges, Fernanda
A1 Santana Penín, María Lourdes
A1 Uriarte Villares, Eugenio
A1 Medda, Rosaria
A1 Pintus, Francesca
A1 Caboni, Martina
A1 Era, Benedetta
A1 Fais, Antonella
A1 Petrillo, Amalia di
K1 3-Arylcoumarins
K1 Condensation reaction
K1 Cross-coupling reaction
K1 Xanthine oxidase inhibitors
K1 Gout
AB In the current paper we studied the interest of a series of 3-arylcoumarin derivatives as xanthine oxidase inhibitors. For the best compound of the series, the 4’-methoxyphenyl-6-nitrocoumarin, it was determined the IC50 value and the type of inhibition. This work is a preliminary screening for further design and synthetize new non-purinergic derivatives as potential compounds involved in the inflammatory suppression, specially related to the gout
PB MDPI
SN 978-3-03842-145-0
YR 2015
FD 2015
LK http://hdl.handle.net/10347/25880
UL http://hdl.handle.net/10347/25880
LA eng
NO Matos, M.J., Borges, F., Santanta, L., Uriarte, E., Medda, R., Pintus, F., Caboni, M., Era, B. Fais, A. & Di Petrillo, A. (2015). Interest of 3-arylcoumarins as xanthine oxidase inhibitors. In J.A. Seijas, M.P. Vázquez Tato & S.K. Lin, Proceedings ECSOC-19: The 19Th International Electronic Conference On Synthetic Organic Chemistry: November 1-30, 2015. MDPI. doi: 10.3390/ecsoc-19-b002
NO The 19th International Electronic Conference on Synthetic Organic Chemistry session Bioorganic, Medicinal and Natural Products Chemistry
DS Minerva
RD 22 abr 2026