RT Journal Article
T1 Neurostructural features predict binge drinking in emerging adulthood: Evidence from a 5-year follow-up study
A1 Pérez García, José Manuel
A1 Suárez Suárez, Samuel
A1 Rodríguez González, María Soledad
A1 Rodríguez Holguín, Socorro
A1 Cadaveira Mahía, Fernando
A1 Doallo Pesado, Sonia
K1 Adolescence
K1 Emerging adulthood
K1 Binge drinking
K1 Prospective longitudinal study
K1 Follow-up
K1 Brain structure
K1 IRM
K1 Adolescencia
K1 Mocidade
K1 Consumo intensivo de alcohol
K1 Seguimento
K1 Estudo lonxitudinal
K1 Estrutura cerebral
K1 Imaxe por resonancia magnética
AB BackgroundBinge drinking (BD) involves consuming large amounts of alcohol within a short timeframe, leading to a blood alcohol concentration of 0.08 g/dL or above. This pattern of alcohol consumption is prevalent among young adults and has significant implications for brain structure and subsequent drinking behaviors.MethodsIn this prospective longitudinal study, we employed zero-inflated negative binomial regression models to examine whether various neurostructural features (i.e., volume, surface area, cortical thickness) of brain regions involved in executive and emotional/motivational processes at the age of 18–19 could predict number of BD episodes five years later, at ages 23–24, once participants were expected to complete their university degree. Specifically, we recorded magnetic resonance imaging (MRI) data from 68 students who completed both the baseline MRI and follow-up alcohol use assessment, with the aim of analyzing the predictive value of these neurostructural characteristics five years later.ResultsThe analysis revealed that a larger surface area in the caudal division of the right middle frontal gyrus was significantly associated with a higher incidence rate of BD episodes (IRR = 2.24, 95 % CI = 1.28–3.91, p = 0.005). Conversely, a smaller surface area in the right caudal anterior cingulate cortex was associated with a higher incidence rate of BD episodes (IRR = 0.61, 95 % CI = 0.44–0.85, p = 0.004).ConclusionsThese findings suggest that specific neurostructural characteristics during adolescence can predict BD behaviors in young adulthood. This highlights the potential of neuroimaging to identify individuals at risk for developing problematic alcohol use.
PB Elsevier
YR 2024
FD 2024
LK https://hdl.handle.net/10347/38713
UL https://hdl.handle.net/10347/38713
LA eng
NO Pérez-García, JM; Suárez-Suárez, S; Rodríguez-González, M.S.; Rodríguez Holguín, S.; Cadaveira, F; Doallo, S. (2024). Neurostructural features predict binge drinking in emerging adulthood: Evidence from a 5-year follow-up study. Drug and Alcohol Dependence,  265, 112489
NO Ministerio de Ciencia, Innovación y Universidades - AEI
NO Xunta de Galicia (GRC ED431C 2021/08)
NO SS-S was supported by a postdoctoral fellowship from the Universidade de Santiago de Compostela co-funded with European Funds (Margarita Salas 2022-2024)
DS Minerva
RD 22 abr 2026