RT Journal Article
T1 Meibomian gland loss area and its relationship with age and ocular surface disease index
A1 García Queiruga, Jacobo
A1 Pena Verdeal, Hugo
A1 Ferreiro Figueiras, Dolores Purificación
A1 García Resúa, Carlos
A1 Yebra-Pimentel Vilar, Eva
K1 Meibomian Glands
K1 Topcon CA-800 topographer
K1 Meibomian gland loss are
K1 MGD
K1 Dry eye symptomatology
K1 ImageJ
AB Purpose: Meibography images bring information about the status and integrity of the meibomian glands (MG). This study aimed to correlate the meibomian gland loss area (MGLA) with age and dry eye symptomatology. Material and methods: A total of 110 subjects were recruited for the study. From the Meibography images obtained with the Topcon® CA-800 topographer, MGLA was calculated as the difference between the total area of the tarsus and the MG presence area measured by using the ImageJ software. Before the examination, all subjects completed an OSDI questionnaire. OSDI scores were grouped in 4 severity categories: normal (score ≤12), mild (score 12–22), moderate (score 22–32) and severe (score ≥32). Age was categorised into 3 subgroups: ≤25 years, from 25 to 45 years and ≥45 years. MGLA was also grouped in 4 categories of loss: ≤25 %, from 25 to 50%, from 50 to 75% and ≥75%. Results: Analysis was performed by dividing the sample into the 4 MGLA subgroups; these subgroups showed age differences (p=0.029; Kruskal-Wallis test) and differences in OSDI scores (p=0.001; Kruskal-Wallis test). The sample was divided into 3 age subgroups and differences were obtained in MGLA values among subgroups (p<0.001; Kruskal-Wallis test). Samples were divided in 4 OSDI subgroups and differences were obtained in MGLA values among subgroups (p=0.003; Kruskal-Wallis test). Positive correlation (Spearman Correlation) was obtained for both, MGLA vs. age (r=0.329, p<0.001) and MGLA vs. OSDI (r=0.380, p<0.001). Conclusion: In the present study MGLA showed a relationship with age and OSDI.
PB SPIE
YR 2019
FD 2019
LK http://hdl.handle.net/10347/32805
UL http://hdl.handle.net/10347/32805
LA eng
NO Jacobo Garcia-Queiruga, Hugo Pena-Verdeal, Dolores Ferreiro, Carlos García-Resua, and Eva Yebra-Pimentel "Meibomian gland loss area and its relationship with age and ocular surface disease index", Proc. SPIE 11207, Fourth International Conference on Applications of Optics and Photonics, 112071B (3 October 2019)
DS Minerva
RD 23 abr 2026