RT Journal Article T1 Impact of Recombinant Bovine Somatotropin on Bovine Milk Composition and Fatty Acidome: A Multidose Longitudinal Study A1 Barreiro, Rocio A1 Lamas Freire, Alexandre A1 Miranda López, José Manuel A1 Franco Abuín, Carlos Manuel A1 Cepeda Sáez, Alberto A1 Regal López, Patricia K1 milk K1 bovine K1 quality K1 composition K1 minerals K1 fatty acid K1 rbST K1 somatotropin AB Somatotropin is a species-specific polypeptide hormone produced in the pituitary gland of vertebrates. When administered exogenously to cattle, it can increase milk yield. However, the trade and administration of recombinant bovine somatotropin (rbST) to farm animals have been banned in the European Union (EU). Aside from food safety issues, very little is known about the effects of this hormone on milk composition and quality. In this work, a wide profile of fatty acids (the so-called fatty acidome) was determined by GC-FID in raw milk collected from control and rbST-treated lactating cows in a multidose longitudinal study. Milk composition (lactose, protein, fat, dry matter), including minerals (Ca, K, Mg, Na, P), was also determined, and milk yield was recorded. A tendency toward a less saturated profile was observed in the milk collected from animals treated with rbST, with higher concentrations of monounsaturated fatty acids. In addition, less calcium and potassium and more lactose and protein content were observed in milk from treated animals than in regular milk. As a result of this multicomponent profiling of milk, a clear impact of somatotropin treatment on milk quality was observed. The obtained results should be particularly interesting for those countries that permit the use of this hormone in dairy production. PB MDPI SN 2304-8158 YR 2022 FD 2022-11-02 LK https://hdl.handle.net/10347/43473 UL https://hdl.handle.net/10347/43473 LA eng NO Barreiro, R.; Lamas, A.; Miranda, J.M.; Franco, C.M.; Cepeda, A.; Regal, P. Impact of Recombinant Bovine Somatotropin on Bovine Milk Composition and Fatty Acidome: A Multidose Longitudinal Study. Foods 2022, 11, 3477. https://doi.org/ 10.3390/foods11213477 DS Minerva RD 23 abr 2026