RT Journal Article
T1 The complete mitogenome of a 500-year-old Inca child mummy
A1 Gómez Carballa, Alberto
A1 Catelli, María Laura
A1 Pardo Seco, Jacobo José
A1 Martinón Torres, Federico
A1 Roewer, Lutz
A1 Vullo, Carlos
A1 Salas Ellacuriaga, Antonio
K1 Genetics
K1 Population genetics
AB In 1985, a frozen mummy was found in Cerro Aconcagua (Argentina). Archaeological studies identified the mummy as a seven-year-old Inca sacrifice victim who lived >500 years ago, at the time of the expansion of the Inca Empire towards the southern cone. The sequence of its entire mitogenome was obtained. After querying a large worldwide database of mitogenomes (>28,000) we found that the Inca haplotype belonged to a branch of haplogroup C1b (C1bi) that has not yet been identified in modern Native Americans. The expansion of C1b into the Americas, as estimated using 203 C1b mitogenomes, dates to the initial Paleoindian settlements (~18.3 thousand years ago [kya]); however, its internal variation differs between Mesoamerica and South America. By querying large databases of control region haplotypes (>150,000), we found only a few C1bi members in Peru and Bolivia (e.g. Aymaras), including one haplotype retrieved from ancient DNA of an individual belonging to the Wari Empire (Peruvian Andes). Overall, the results suggest that the profile of the mummy represents a very rare sub-clade that arose 14.3 (5–23.6) kya and could have been more frequent in the past. A Peruvian Inca origin for present-day C1bi haplotypes would satisfy both the genetic and paleo-anthropological findings.
PB Nature Publishing Group
SN 2045-2322
YR 2015
FD 2015
LK http://hdl.handle.net/10347/23021
UL http://hdl.handle.net/10347/23021
LA eng
NO Gómez-Carballa, A., Catelli, L., Pardo-Seco, J. et al. The complete mitogenome of a 500-year-old Inca child mummy. Sci Rep 5, 16462 (2015). https://doi.org/10.1038/srep16462
NO The research leading to these results has received funding from the “Ministerio de Ciencia e Innovación”(SAF2011–26983), the Plan Galego IDT (EM 2012/045) and a grant from the Sistema UniversitarioGallego- Modalidad REDES (2012-PG226) from the Xunta de Galicia (A.S.); Instituto Carlos III(Intensificación de la actividad investigadora) and Fondo de Investigación Sanitaria (FIS; PI10/00540and PI13/02382) of the Plan Nacional de I+ D+ I and Fondos FEDER (F.M.T)
DS Minerva
RD 24 abr 2026