RT Journal Article
T1 Rhodium(III)‐Catalyzed Annulation of 2‐Alkenylanilides with Alkynes via C‐H Activation: a Direct Access to 2‐substituted Indolines
A1 Font Molíns, Marc
A1 Cendón Mariño, Borja
A1 Seoane Fernández, Andrés
A1 Mascareñas Cid, José Luis
A1 Gulías Costa, Moisés
K1 C-H activation
K1 Annulation
K1 Rhodium
K1 Catalysis
AB A Rh(III) complex featuring an electron‐deficient η5‐cyclopentadienyl ligand catalyzes an unusual annulation between alkynes and 2‐alkenylanilides, to form synthetically appealing 2‐substituted indolines. Formally, the process can be viewed as an allylic amination with concomitant hydrocarbonation of the alkyne. Mechanistic experiments indicate that this transformation involves a peculiar Rhodium migration with a concomitant 1,5‐H shift
PB Wiley
SN 1521-3757
YR 2018
FD 2018-05-04
LK http://hdl.handle.net/10347/16765
UL http://hdl.handle.net/10347/16765
LA eng
NO Font, M., Cendón, B., Seoane, A., Mascareñas, J., & Gulías, M. (2018). Rhodium(III)-Catalyzed Annulation of 2-Alkenyl Anilides with Alkynes through C−H Activation: Direct Access to 2-Substituted Indolines. Angewandte Chemie International Edition. doi: 10.1002/anie.201802830
NO This  work  has  received  financial  support  from  Spanish  grants (SAF2016-76689-R  and  CTQ2016-77047-P),  the  Xunta  de Galicia (ED431C 2017/19, 2015-CP082 and Centro Singular de Investigación  de  Galicia  accreditation  2016-2019,  ED431G/09) the  European  Regional  Development  Fund  (ERDF),  and  the European Research Council (Advanced Grant No. 340055). The orfeo-cinqa  network  CTQ2016-81797-REDC  is  also  kindly acknowledged
DS Minerva
RD 24 abr 2026