RT Journal Article
T1 Mapping the genomic mosaic of two ‘Afro-Bolivians’ from the isolated Yungas valleys
A1 Pardo Seco, Jacobo José
A1 Heinz, Tanja Maria
A1 Taboada Echalar, Patricia
A1 Martinón Torres, Federico
A1 Salas Ellacuriaga, Antonio
K1 Transatlantic slave trade
K1 Afro-Bolivians
K1 Ancestry
K1 Genome
K1 SNPs
AB Background: Unraveling the ancestry of ‘Afro-American’ communities is hampered by the complex demographicprocesses that took place during the Transatlantic Slave Trade (TAST) and the (post-)colonization periods. ‘AfroBolivians’from the subtropical Yungas valleys constitute small and isolated communities that live surrounded bythe predominant Native American community of Bolivia. By genotyping >580,000 SNPs in two ‘Afro-Bolivians’, andcomparing these genomic profiles with data compiled from more than 57 African groups and other referenceancestral populations (n = 1,161 in total), we aimed to disentangle the complex admixture processes undergone by‘Afro-Bolivians’.Results: The data indicate that these two genomes constitute a complex mosaic of ancestries that is approximately80 % of recent African origin; the remaining ~20 % being European and Native American. West-Central Africacontributed most of the African ancestry to ‘Afro-Bolivians’, and this component is related to populations living alongthe Atlantic coast (i.e. Senegal, Ghana, Nigeria). Using tract length distribution of genomic segments attributable todistinct ancestries, we could date the time of admixture in about 400 years ago. This time coincides with the maximumimportation of slaves to Bolivia to compensate the diminishing indigenous labor force needed for the development ofthe National Mint of Potosí.Conclusions: Overall, the data indicate that the genome of ‘Afro-Bolivians’ was shaped by a complex process ofadmixture occurring in America among individuals originating in different West-Central African populations; theirgenomic mosaics received additional contributions of Europeans and local Native Americans (e.g. Aymaras)
PB BioMed Central
SN 1471-2164
YR 2016
FD 2016-03-09
LK http://hdl.handle.net/10347/15915
UL http://hdl.handle.net/10347/15915
LA eng
NO Pardo-Seco, Jacobo, Tanja Heinz, Patricia Taboada-Echalar, Federico Martinón-Torres, and Antonio Salas. 2016. "Mapping The Genomic Mosaic Of Two ‘Afro-Bolivians’ From The Isolated Yungas Valleys". BMC Genomics 17 (1). doi:10.1186/s12864-016-2520-x
NO The research leading to these results has received funding from the People Program (Marie Curie Actions) of the European Union’s Seventh Framework Program FP7/2007–2013/under REA grant agreement no. 290344, from the “Ministerio de Ciencia e Innovación” (SAF2011–26983), the “Plan Galego IDT” (EM 2012/045) and the grant from the “Sistema Universitario Gallego- Modalidad REDES (2012-PG226) from the Xunta de Galicia (A.S.). F.M-T received support from the grant “ISCIII/INT14/00245/ Cofinanciado FEDER"
DS Minerva
RD 23 abr 2026