RT Journal Article
T1 Metal-catalyzed Cyclizations to Pyran and Oxazine Derivatives
A1 Varela Carrete, Jesús Ángel
A1 Saá Rodríguez, Carlos
K1 Allenols
K1 Bis-homopropargyl alcohols
K1 Catalysis
K1 Cyclizations
K1 Heterocyclizations
K1 1,4-Oxazines
K1 Pyrans
K1 Transition metals
AB Pyrans are privileged heterocyclic structures found in numerous natural compounds with extraordinary biological activities. The synthesis of these relevant structures has attracted a great deal of attention over the years. Catalytic methodologies based on the activation of neutral unsaturated functionalities of acyclic compounds that undergo intramolecular cyclizations have achieved prominent synthetic relevance. In this short review, we discuss the successful construction of dihydropyran and dihydro-1,4-oxazine derivatives from acyclic precursors by metal-catalyzed intramolecular cyclizations through carbon–carbon, carbon–oxygen, and carbon–nitrogen bond formation. Remarkable synthetic applications are highlighted.
PB Thieme
SN 0039-7881
YR 2016
FD 2016
LK http://hdl.handle.net/10347/23350
UL http://hdl.handle.net/10347/23350
LA eng
NO Varela, J. A., Saá, C. (2016). Metal-catalyzed Cyclizations to Pyran and Oxazine Derivatives. Synthesis, 48, 20, 3470-3478
NO NOTICE: This is the peer reviewed version of the following article: Varela, J. A., Saá, C. (2016). Metal-catalyzed Cyclizations to Pyran and Oxazine Derivatives. Synthesis, 48, 20, 3470-3478. [doi: 10.1055/s-0035-1562466]. This article may be used for non-commercial purposes in accordance with Thieme Terms and Conditions for self-archiving.
NO This work was supported by the Spanish MINECO (project CTQ2014-59015R), the Xunta de Galicia (project GRC2014/032) and the European Regional Development Fund (projects CTQ2014-59015R and GRC2014/032). We also thank the ORFEO-CINQA network (CTQ2014-51912REDC)
DS Minerva
RD 24 abr 2026