RT Journal Article
T1 Resveratrol-based biorefinery models for favoring its inclusion along the market value-added chains: A critical review
A1 Arias Calvo, Ana
A1 Costa, Carlos E.
A1 Moreira Vilar, María Teresa
A1 Feijoo Costa, Gumersindo
A1 Domingues, Lucília
K1 Resveratrol
K1 Renewable resources
K1 Extraction techniques
K1 Biorefinery
K1 Circular economy
K1 Market value chain
AB Resveratrol, a natural organic polyhydroxyphenolic compound, has gained significant attention in the last years given its potential health benefits, including antioxidant, anti-cancer, and anti-inflammatory properties. It can be directly extracted from plants, vegetables, and related products and waste resources, but also chemically/enzymatically/microbially synthesized. However, certain process strategies have some limitations, such as high costs, reduced yield or high energy demand, thus implying significant environmental loads. In this context, the search for more sustainable and circular process schemes is key to the integration of resveratrol into the market value chain of the food, cosmetic and pharmaceutical sectors. The extraction of resveratrol has traditionally been based on conventional methods such as solvent extraction, but advanced green extraction techniques offer more efficient and environmentally friendly alternatives. This review analyses both conventional and green alternative extraction technologies, as well as its bioproduction through microbial fermentation, in terms of production capacity, yield, purity and sustainability. It also presents alternative biorefinery models based on resveratrol bioproduction using by-products and waste streams as resources, specifically considering wine residues, peanut shells and wood bark as input resources, and also following a circular approach. This critical review provides some insight into the opportunities that resveratrol offers for promoting sustainable development and circularity in the related market value chains, and thus provides some criteria for decision making for biorefinery models in which resveratrol is one of the targeted high value-added products. It also identifies the future challenges to promote the inclusion of resveratrol in value chains, with the scale-up of green technologies and its demonstrated economic feasibility being the most prominent
PB Elsevier
SN 0048-9697
YR 2024
FD 2024
LK http://hdl.handle.net/10347/33171
UL http://hdl.handle.net/10347/33171
LA eng
NO Science of The Total Environment, Volume 908, 2024, 168199
NO This study was supported by the Portuguese Foundation for Science and Technology (FCT, Portugal) under the scope of the strategic funding of UIDB/04469/2020 and ESSEntial project (PTDC/BII-BTI/1858/2021). A. Arias, G. Feijoo and MT Moreira authors belong to the Galician Competitive Research Group (GRC ED431C 2021/37) and to the Cross-disciplinary Research in Environmental Technologies (CRETUS Research Center, ED431E 2018/01). A. Arias would also like to express her gratitude to the IACOBUS programme for the fellowship provided for the development of one-month research stay at the University of Minho
DS Minerva
RD 24 abr 2026