RT Journal Article T1 Titanium vs ceramic single dental implants in the anterior maxilla: A 12-month randomized clinical trial A1 Ruiz Henao, Paula Andrea A1 Caneiro Queija, Leticia A1 Mareque Bueno, Santiago A1 Tasende Pereira, Almudena A1 Liñares, Antonio A1 Blanco Carrión, Juan K1 Dental implants K1 Esthetics K1 Humans K1 Randomized controlled trial K1 Zirconium AB ObjectiveThe aim of this randomized clinical trial was to compare ceramic and titanium implants with respect to the esthetic and clinical parameters, and patient-reported outcome measures (PROMs).Material and methodsThirty patients received thirty implants (8–12 mm in length, 3.3 mm diameter, and a tissue level design) to replace single teeth in the anterior maxilla. Patients were randomly allocated to receive a ceramic or a titanium implant. Esthetic, clinical parameters, and PROMs were evaluated 18 months after surgery.ResultsAt 12 months post-final loading, there were no significant differences between groups with respect to esthetics. Mean Index Crown Aesthetic score was 6.31 (95% C.I. 4.59–8.04) and 6.07 (95% C.I. 4.21–7.93) for ceramic and titanium implants, respectively. The pink esthetic score (PES) was 7.81 (95% C.I. 6.90–8.73) for ceramic implants and 7.86 (95% C.I. 7.11–8.60) for titanium implants, with no significant differences between groups. No statistically significant differences were found for any of the other clinical parameters and PROMs.ConclusionsMonotype ceramic implants have proven to be a good treatment option in the upper anterior sector, showing favorable esthetic results, being comparable to titanium implants.This clinical trial has been registered in clinical trials with the identifier CI_RCT_US16 and registration number NCT04707677. A retrospective registration of the clinical trial was carried out since registration was not mandatory on the date the study began PB Wiley SN 0905-7161 YR 2021 FD 2021-06-01 LK https://hdl.handle.net/10347/41307 UL https://hdl.handle.net/10347/41307 LA eng NO Ruiz Henao, P. A., Caneiro Queija L.,Mareque S., Tasende Pereira A., Liñares González A., & BlancoCarrión J. Titanium vs ceramic single dental implants in theanterior maxilla: A 12-month randomized clinical trial. ClinicalOral Implants Research, 2021;32:951–961. https://doi.org/10.1111/clr.13788 DS Minerva RD 1 may 2026