RT Journal Article
T1 Impact of anxiety and depression on the prognosis of copd exacerbations
A1 Martínez Gestoso, Sandra
A1 García Sanz, María Teresa
A1 Carreira Villamor, José Martin
A1 Salgado Castro, Francisco Javier
A1 Calvo Álvarez, Uxío
A1 Doval Oubiña, Liliana
A1 Camba Matos, Sandra
A1 Peleteiro Pedraza, Lorena
A1 González Pérez, Miguel Ángel
A1 Penela Penela, Pedro
A1 Vilas Iglesias, Andrés
A1 González Barcala, Francisco Javier
K1 COPD
K1 Anxiety
K1 Depression
K1 Prognosis
AB BackgroundFrequent and highly prevalent as comorbidities in Chronic Obstructive Pulmonary Disease (COPD) patients, both depression and anxiety seem to have an impact on COPD prognosis. However, they are underdiagnosed and rarely treated properly.AimTo establish the prevalence of depression and anxiety in patients admitted for Acute Exacerbation of COPD (AECOPD) and determine their influence on COPD prognosis.MethodsProspective observational study conducted from October 1, 2016 to October 1, 2018 at the following centers in Galicia, Spain: Salnés County Hospital, Arquitecto Marcide, and Clinic Hospital Complex of Santiago de Compostela. Patients admitted for AECOPD who agreed to participate and completed the anxiety and depression scale (HADS) were included in the study.Results288 patients (46.8%) were included, mean age was 73.7 years (SD 10.9), 84.7% were male. 67.7% patients were diagnosed with probable depression, and depression was established in 41.7%; anxiety was probable in 68.2% and established in 35.4%. 60.4% of all patients showed symptoms of both anxiety and depression. Multivariate analysis relates established depression with a higher risk of late readmission (OR 2.06, 95% CI 1.28; 3.31) and a lower risk of mortality at 18 months (OR 0.57, 95% CI 0.37; 0.90).ConclusionThe prevalence of anxiety and depression in COPD patients is high. Depression seems to be an independent factor for AECOPD, so early detection and a multidisciplinary approach could improve the prognosis of both entities. The study was approved by the Ethical Committee of Galicia (code 2016/460)
PB BMC
SN 1471-2466
YR 2022
FD 2022-04-29
LK https://hdl.handle.net/10347/40449
UL https://hdl.handle.net/10347/40449
LA eng
NO Martínez-Gestoso, S., García-Sanz, MT., Carreira, JM. et al. Impact of anxiety and depression on the prognosis of copd exacerbations. BMC Pulm Med 22, 169 (2022). https://doi.org/10.1186/s12890-022-01934-y
DS Minerva
RD 28 abr 2026