RT Journal Article
T1 Non-surgical treatment of periodontal disease in a pregnant caucasian women population: adverse pregnancy outcomes of a randomized clinical trial
A1 Caneiro Queija, Leticia
A1 López Carral, José Manuel
A1 Martín Lancharro, Pablo
A1 Limeres Posse, Jacobo
A1 Diz Dios, Pedro
A1 Blanco Carrión, Juan
K1 Preterm birth
K1 Low birth weight
K1 Pregnancy
K1 Periodontal disease
AB Aim: To analyze if non-surgical treatment of periodontitis in a pregnant Caucasian women population can reduce adverse pregnancy outcomes. Methods and results: A parallel randomized clinical trial was designed and approved by the Ethical Committee of Sanitary Area Santiago-Lugo, Spain (registration number: 2016/451). Forty patients with periodontitis stage II grade B were randomly allocated to receive either comprehensive non-surgical periodontal therapy (test group; n = 20) or professional tooth cleaning (control group; n = 20) before 24 gestational weeks. Randomization was computer-generated by the statistic program Epidat v.4.1 and allocation was performed using sealed opaque envelopes. Clinical measurements and peripheral blood samples for biochemical variables were collected at baseline, in the middle of second trimester before non-surgical treatment, and in the third trimester. Microbiological samples were collected in the second and third trimester. A statistically significant reduction was verified in all clinical and microbiological parameters after periodontal treatment in the test group. No significant differences were observed for the rest of the variables, including preterm birth and/or low birth weight. No adverse events related to periodontal treatment were reported. Conclusions: Non-surgical periodontal treatment in Caucasian patients with periodontitis stage II grade B did not significantly reduce the risk of adverse pregnancy outcomes.
PB MDPI
SN 1661-7827
YR 2019
FD 2019
LK http://hdl.handle.net/10347/21177
UL http://hdl.handle.net/10347/21177
LA eng
NO Caneiro-Queija, L.; López-Carral, J.; Martin-Lancharro, P.; Limeres-Posse, J.; Diz-Dios, P.; Blanco-Carrion, J. Non-Surgical Treatment of Periodontal Disease in a Pregnant Caucasian Women Population: Adverse Pregnancy Outcomes of a Randomized Clinical Trial. Int. J. Environ. Res. Public Health 2019, 16, 3638.
DS Minerva
RD 24 abr 2026