RT Journal Article
T1 New Perspectives in Neuroprotection for Ischemic Stroke
A1 Pérez Mato, María
A1 López Arias, Esteban
A1 Bugallo Casal, Ana
A1 Correa Paz, Clara
A1 Arias, Susana
A1 Rodríguez‐Yáñez, Manuel
A1 Santamaría Cadavid, María
A1 Campos Pérez, Francisco
K1 Biomarkers
K1 Early diagnosis
K1 Ischemic stroke
K1 Neuroprotection
K1 Recanalization therapies
AB The constant failure of new neuroprotective therapies for ischemic stroke has partially halted the search for new therapies in recent years, mainly because of the high investment risk required to develop a new treatment for a complex pathology, such as stroke, with a narrow intervention window and associated comorbidities. However, owing to recent progress in understanding the stroke pathophysiology, improvement in patient care in stroke units, development of new imaging techniques, search for new biomarkers for early diagnosis, and increasingly widespread use of mechanical recanalization therapies, new opportunities have opened for the study of neuroprotection. This review summarizes the main protective agents currently in use, some of which are already in the clinical evaluation phase. It also includes an analysis of how recanalization therapies, new imaging techniques, and biomarkers have improved their efficacy.
PB Elsevier
SN 0306-4522
YR 2024
FD 2024
LK http://hdl.handle.net/10347/34597
UL http://hdl.handle.net/10347/34597
LA eng
NO Neuroscience Volume 550 , 9 July 2024, Pages 30-42
NO This project was supported by the grant “Proyecto Consolidación Xunta de Galicia, Spain” (GAIN_IN607A2022/02).
DS Minerva
RD 24 abr 2026