RT Journal Article
T1 Ruthenium catalysis in biological habitats
A1 Gutiérrez González, Alejandro
A1 López García, Fernando José
A1 Mascareñas Cid, José Luis
K1 Bioconjugation
K1 Bioorthogonal chemistry
K1 Fluorescence
K1 Organometallic chemistry
K1 Transition metals
AB Recent years have witnessed a considerable progress in research aimed at merging transition metal catalysis with chemical and cell biology. Therefore, a crescent number of metal-catalyzed transformations have been shown compatible with biological media and even with living settings. Of the different transition metals used to build these biocompatible catalysts, ruthenium has demonstrated to be particularly powerful, in part because the resulting complexes exhibit a very good balance between reactivity and biological stability. Indeed, ruthenium complexes have demonstrated utility to promote a great variety of reactions in biologically relevant contexts, from deprotection and redox processes to cycloadditions or photocatalytic transformations. Many of these reactions may enable the development of new type of biological tools and pharmacological strategies
PB Wiley
SN 0018-019X
YR 2023
FD 2023
LK http://hdl.handle.net/10347/30679
UL http://hdl.handle.net/10347/30679
LA eng
NO Gutiérrez-González, A., López, F., Mascareñas, J. L., Helv. Chim. Acta 2023, 106, e202300001
NO Dedicated to Prof. Janine Cossy
NO PID2020-118579GB−I00; PID2019-108624RB−I00; Consellería de Cultura, Educación e Ordenación Universitaria-Grant Numbers: ED431 C 2021/25, ED431G 2019/03; European Union; Ministerio de Universidades. Grant Number: FPU17/00711
DS Minerva
RD 28 abr 2026