RT Journal Article
T1 Effectiveness of smoking cessation interventions among pregnant women: An updated systematic review and meta-analysis
A1 Vila Fariñas, Andrea
A1 Pérez Ríos, Mónica
A1 Montes Martínez, Agustín
A1 Ruano Raviña, Alberto
A1 Forray, Ariadna
A1 Rey Brandariz, Julia
A1 Candal Pedreira, Cristina
A1 Fernández, Esteve
A1 Casal Acción, Beatriz
A1 Varela Lema, María Leonor
K1 Pregnancy
K1 Interventions
K1 Smoking
K1 Cessation
K1 Meta-analysis
K1 Systematic review
AB Objective: To carry out a systematic review of systematic reviews with an update of the existing evidence relating to a broad range of smoking cessation interventions, including psycho-social, digital and pharmacologic interventions, for pregnant women. Data-sources: Search was conducted in March 2022 in PubMed, EMBASE, and Cochrane in two stages: 1) a search of systematic reviews and meta-analyses, published from January 2012 through January 2022; 2) an update of those that fulfilled eligibility criteria reproducing the primary search strategy. Study eligibility criteria: We selected randomized clinical trials (RCTs) that evaluated the effectiveness of pharmacological, digital, and psychosocial interventions in aged 18 years and over who were daily smokers, and compared these with routine care, less intense interventions or placebo. Study appraisal and synthesis methods: Data from eligible studies were manually extracted by two authors and reviewed by a third. The quality of the reviews was evaluated using the AMSTAR scale, and risk of bias was measured with the Rob-2 tool and GRADE level of evidence. Results: The meta-analysis included 63 RCTs (n = 19849 women). The interventions found to be effective were: financial incentives (RR:1.77; 95%CI:1.21–2.58), counseling (RR:1.27; 95%CI:1.13–1.43) and long-term nicotine replacement therapy (NRT) (RR:1.53; 95%CI:1.16–2.01). Short-term NRT, bupropion, digital interventions, feedback, social support, and exercise showed no effectiveness. The GRADE level of evidence was moderate-tohigh for all interventions, with the exception of long-term NRT. Conclusions: Non-pharmacological interventions for smoking cessation are the most effective for pregnant women. The moderator analysis suggests that pregnant women of low socioeconomic status might benefit less from smoking cessation interventions than women of a high socioeconomic status. These women are usually heavier smokers that live in pro-smoking environments and could require more intensive and targeted interventions
PB Elsevier
SN 0306-4603
YR 2024
FD 2024
LK http://hdl.handle.net/10347/32951
UL http://hdl.handle.net/10347/32951
LA eng
NO Addictive Behaviors, Volume 148, 2024, 107854
DS Minerva
RD 28 abr 2026