RT Journal Article
T1 Anion Recognition as a Supramolecular Switch of Cell Internalization
A1 Rodríguez Villar, Jéssica
A1 Mosquera Mosquera, Jesús
A1 Rodríguez Couceiro, José
A1 Nitschke, Jonathan R.
A1 Vázquez Sentís, Marco Eugenio
A1 Mascareñas Cid, José Luis
AB The cell internalization of designed oligoarginine peptides equipped with six glutamic acid residues and an anionic pyranine at the N-terminus is triggered upon addition of a supramolecular host. This host binds specifically to the pyranine moiety, enabling the complex to traverse the cell membrane. Interestingly, none of the components, neither the host nor the guest, are able to cross the cell membrane on their own
PB American Chemical Society
SN 0002-7863
YR 2016
FD 2016
LK http://hdl.handle.net/10347/18481
UL http://hdl.handle.net/10347/18481
LA eng
NO Rodríguez, J., Mosquera, J., Couceiro, J., Nitschke, J., Vázquez, M., & Mascareñas, J. (2016). Anion Recognition as a Supramolecular Switch of Cell Internalization. Journal Of The American Chemical Society, 139(1), 55-58. doi: 10.1021/jacs.6b11103
NO We are thankful for the support given by the Spanish grants SAF2013-41943-R, CTQ2015-70698-R, and CTQ2013-49317-EXP, the Consellerı́a de Cultura, Educación e Ordenación Universitaria (GRC2013-041 and Centro singular de investigación de Galicia accreditation 2016-2019, ED431G/09), the European Regional Development Fund (ERDF), and the European Research Council (Advanced Grant No. 340055). Support of the orfeo-cinqa network (CTQ2014-51912-REDC) is kindly acknowledged. J.R. thanks the Xunta de Galicia for her Ph.D. fellowship, and J.M. thanks Fundación Ramón Areces for his postdoctoral fellowship
DS Minerva
RD 28 abr 2026