RT Dissertation/Thesis
T1 Self-Assembly of Synthetic and Biological Polymeric Systems of Technological Interest
A1 Juárez Onofre, Josué Elías
K1 Block copolymers
K1 Human serum albumin
K1 Amyloid fibrils
K1 Metallic nanoparticles
K1 Biotemplates
AB In the present work, we investigated the micellization, gelation and the structure of aggregates ofthree poly(ethylene oxide)-poly(styrene oxide)-poly(ethylene oxide) block copolymers (EO12SO10,EO10SO10E10 and EO137SO18EO137, where E represents the oxyethylene unit, S the oxystyrene unit,and the subscripts correspond to the number of monomeric unit constituting the polymeric chain)in solution. We also investigated the adsorption process and the surface properties of these blockcopolymers at the air-water (a/w) and chloroform-water (c/w) interfaces. Since these copolymerspossess a more hydrophobic middle block –the styrene oxide unit, they should gives rise to moreefficient drug delivery systems, in which geometry might play a key role for drug solubilisation andcell uptake. For these reasons, a detailed characterization of the physicochemical properties ofthese copolymers is required.
YR 2012
FD 2012-06-08
LK http://hdl.handle.net/10347/5132
UL http://hdl.handle.net/10347/5132
LA eng
DS Minerva
RD 24 abr 2026