RT Journal Article
T1 First Report of Ciguatoxins in Two Starfish Species: Ophidiaster ophidianus and Marthasterias glacialis
A1 Silva, Marisa
A1 Rodríguez Filgueiras, Inés
A1 Barreiro, Aldo
A1 Kaufmann, Manfred
A1 Neto, Ana Isabel
A1 Hassouani, Meryem
A1 Sabour, Brahim
A1 Alfonso Rancaño, María Amparo
A1 Botana López, Luis Miguel
A1 Vasconcelos, Vitor
K1 Ciguatera
K1 New vectors
K1 Madeira Island
K1 São Miguel Island
K1 Morocco
AB Ciguatera fish poisoning (CFP) is a syndrome caused by the ingestion of fish contaminated with Ciguatoxins (CTXs). These phycotoxins are produced mainly by dinoflagellates that belong to the genus Gambierdiscus that are transformed in more toxic forms in predatory fish guts, and are more present in the Indo-Pacific and Caribbean areas. It is estimated that CFP causes per year more than 10,000 intoxications worldwide. With the rise of water temperature and anthropogenic intervention, it is important to study the prevalence of CFP in more temperate waters. Through inter- and subtidal sampling, 22 species of organisms were collected, in Madeira and Azores archipelagos and in the northwestern Moroccan coast, during September of 2012 and June and July of 2013. A total of 94 samples of 22 different species of bivalves, gastropods, echinoderms and crustaceans where analyzed by Ultra Performance Liquid Chromatography-Mass Spectometry-Ion Trap-Time of Flight (UPLC-MS-IT-TOF) and Ultra Performance Chromatography- Mass Spectrometry (UPLC-MS). Our main aim was to detect new vectors and ascertain if there were some geographical differences. We detected for the first time putative CTXs in echinoderms, in two starfish species—M. glacialis and O. ophidianus. We detected differences regarding uptake values by organisms and geographical location. Toxin amounts were significant, showing the importance and the need for continuity of these studies to gain more knowledge about the prevalence of these toxins, in order to better access human health risk. In addition, we suggest monitoring of these toxins should be extended to other vectors, starfish being a good alternative for protecting and accessing human health risk
PB MDPI
YR 2015
FD 2015
LK http://hdl.handle.net/10347/23586
UL http://hdl.handle.net/10347/23586
LA eng
NO Silva, M.; Rodriguez, I.; Barreiro, A.; Kaufmann, M.; Neto, A.I.; Hassouani, M.; Sabour, B.; Alfonso, A.; Botana, L.M.; Vasconcelos, V. First Report of Ciguatoxins in Two Starfish Species: Ophidiaster ophidianus and Marthasterias glacialis. Toxins 2015, 7, 3740-3757
NO This research was partially funded by the FCT project UID/Multi/04423/2013 and by the projects MARBIOTECH (reference NORTE-07-0124-FEDER-000047) within the SR&TD Integrated Program MARVALOR—Building research and innovation capacity for improved management and valorization of marine resources, supported by the Programa Operacional Regional do Norte (ON.2-O Novo Norte) and NOVOMAR (reference 0687-NOVOMAR-1-P), supported by the European Regional Development Fund. M.S. also acknowledges FCT for the grant SFRH/BD/73269/2010 and Ana Regueiras, Isadora Diniz, Afonso Prestes and Manuela Maranhão. This research was also partially funded by the FCT-Portugal/CNRST-Morocco Cooperation Convention under the project 1006/13 CNR “Marine emergent toxins in the north east Atlantic (Portugal-Morocco) produced by microalgae and bacteria”. I. R. was supported by a fellowship from Subprograma de Formación de Personal Investigador (AGL2012-40185-CO2-01), Spain. The research leading to these results has received funding from the following FEDER cofunded-grants. From CDTI and Technological Funds, supported by Spanish Ministerio de Economía y Competitividad, AGL2012-40185-CO2-01, AGL2014-58210-R, and Consellería de Cultura, Educación e Ordenación Universitaria, GRC2013-016 (Galicia) Spain
DS Minerva
RD 24 abr 2026