RT Journal Article T1 Decision Making Impairment: A Shared Vulnerability in Obesity, Gambling Disorder and Substance Use Disorders? A1 Mallorquí Bagué, Nuria A1 Fagundo, Ana Beatriz A1 Jiménez Murcia, Susana A1 Torre, Rafael de la A1 Baños, Rosa M. A1 Botella, Cristina A1 Casanueva Freijo, Felipe A1 Crujeiras Martínez, Ana Belén A1 Fernández García, José C. A1 Fernández Real, José Manuel A1 Frühbeck, Gema A1 Granero, Roser A1 Rodríguez, Amaia A1 Tolosa Sola, Iris A1 Ortega, Francisco J. A1 Tinahones Madueño, Francisco José A1 Álvarez Moya, Eva A1 Ochoa, Cristian A1 Menchón, José M. A1 Fernández Aranda, Fernando K1 Decision making K1 Learning K1 Cognitive impairment K1 Behavioral addiction K1 Obesity K1 Addiction K1 Gambling K1 Neuropsychological testing AB IntroductionAddictions are associated with decision making impairments. The present study explores decision making in Substance use disorder (SUD), Gambling disorder (GD) and Obesity (OB) when assessed by Iowa Gambling Task (IGT) and compares them with healthy controls (HC).MethodsFor the aims of this study, 591 participants (194 HC, 178 GD, 113 OB, 106 SUD) were assessed according to DSM criteria, completed a sociodemographic interview and conducted the IGT.ResultsSUD, GD and OB present impaired decision making when compared to the HC in the overall task and task learning, however no differences are found for the overall performance in the IGT among the clinical groups. Results also reveal some specific learning across the task patterns within the clinical groups: OB maintains negative scores until the third set where learning starts but with a less extend to HC, SUD presents an early learning followed by a progressive although slow improvement and GD presents more random choices with no learning.ConclusionsDecision making impairments are present in the studied clinical samples and they display individual differences in the task learning. Results can help understanding the underlying mechanisms of OB and addiction behaviors as well as improve current clinical treatments. PB Plos YR 2016 FD 2016 LK http://hdl.handle.net/10347/22997 UL http://hdl.handle.net/10347/22997 LA eng NO Mallorquí-Bagué N, Fagundo AB, Jimenez-Murcia S, de la Torre R, Baños RM, Botella C, et al. (2016) Decision Making Impairment: A Shared Vulnerability in Obesity, Gambling Disorder and Substance Use Disorders? PLoS ONE 11(9): e0163901. https://doi.org/10.1371/journal.pone.0163901 NO This manuscript was supported by grants from Instituto Salud Carlos III (ISCIII; FIS PI14/00290 and CIBERobn) and co-funded by Fondos Europeos de Desarrollo Regional (FEDER) funds - a way to build Europe, and AGAUR (2014 SGR 1672). This manuscript was co-funded by Ministerio de Economía y Competitividad (PSI2015-68701-R). CIBERobn and CIBERSAM are both initiatives of ISCIII. Jose C. Fernández-García is recipient of a research contract from Servicio Andaluz de Salud (SAS) (B-0033-2014) DS Minerva RD 27 abr 2026