RT Journal Article T1 Bottom-up supramolecular assembly in two dimensions A1 Insua López, Ignacio A1 Bergueiro Álvarez, Julián A1 Méndez Ardoy, Alejandro A1 Lostalé Seijo, Irene A1 Montenegro García, Javier AB The self-assembly of molecules in two dimensions (2D) is gathering attention from all disciplines across the chemical sciences. Attracted by the interesting properties of two-dimensional inorganic analogues, monomers of different chemical natures are being explored for the assembly of dynamic 2D systems. Although many important discoveries have been already achieved, great challenges are still to be addressed in this field. Hierarchical multicomponent assembly, directional non-covalent growth and internal structural control are a just a few of the examples that will be discussed in this perspective about the exciting present and the bright future of two-dimensional supramolecular assemblies PB Royal Society of Chemistry SN 1478-6524 YR 2022 FD 2022 LK http://hdl.handle.net/10347/30330 UL http://hdl.handle.net/10347/30330 LA eng NO Chem. Sci., 2022, 13, 3057. https://doi.org/10.1039/D1SC05667K NO This article is part of the themed collections: Most popular 2022 supramolecular chemistry articles and 2022 Chemical Science Perspective & Review Collection NO This work was partially supported by the Spanish Agencia Estatal de Investigación (AEI) (SAF2017-89890-R, PCI2019-103400, and PID2020-117143RB-I00), Xunta de Galicia (ED431C 2017/25, Centro singular de investigación de Galicia accreditation 2019–2022, ED431G 2019/03) and the European Commission (ERDF). I. I. thanks the European Commission (EC) and AEI for MSCA-IF (2018-843332) and Juan de la Cierva (FJCI-2017-31795) fellowships, respectively. J. M. thanks the ERC-STG (DYNAP, 677786), Instituto de Salud Carlos III (COV20/00297), ERC-POC (TraffikGene, 838002), Xunta de Galicia (Oportunius Program) and Human Frontier Science Programme Young Investigator Grant (RGY0066/2017) for funding DS Minerva RD 3 may 2026