RT Book,_Section
T1 The Reactions of Mitomycin C with Dithiols I. Reductive Activation
A1 Paz Castañal, Manuel María
AB We report that the clinically used antitumor drug mitomycin C is reductively activated in vitro by simple thiols; a mechanism for this activation is proposed based on kinetic data and the identification of mitosene metabolites. The biological implications of these findings are discussed
PB MDPI
SN 3-906980-24-3
YR 2010
FD 2010
LK http://hdl.handle.net/10347/26882
UL http://hdl.handle.net/10347/26882
LA eng
NO Proceedings of the 14th International Electronic Conference on Synthetic Organic Chemistry, 1–30 November 2010, MDPI: Basel, Switzerland, doi:10.3390/ecsoc-14-00482
NO The 14th International Electronic Conference on Synthetic Organic Chemistry session Natural Products Chemistry
DS Minerva
RD 29 abr 2026