RT Journal Article
T1 Influence of binge drinking on the resting state functional connectivity of university Students: A follow-up study
A1 Suárez Suárez, Samuel
A1 Cadaveira Mahía, Fernando
A1 Barrós Loscertales, Alfonso
A1 Pérez García, José Manuel
A1 Rodríguez Holguín, Socorro
A1 Blanco-Ramos, Javier
A1 Doallo Pesado, Sonia
K1 Binge drinking
K1 Resting-state
K1 Functional magnetic resonance imaging
K1 Functional connectivity
K1 Adolescence
K1 Consumo intensivo de alcohol
K1 Estado de respouso
K1 Resonancia magnética funcional
K1 Conectividade funcional
K1 Adolescencia
K1 IRMf
K1 fRMI
AB Binge Drinking (BD) is characterized by consuming large amounts of alcohol on one occasion, posing risks to brain function. Nonetheless, it remains the most prevalent consumption pattern among students. Cross-sectional studies have explored the relationship between BD and anomalies in resting-state functional connectivity (RS-FC), but the medium/long-term consequences of BD on RS-FC during developmental periods remain relatively unexplored. In this two-year follow-up study, the impact of sustained BD on RS-FC was investigated in 44 college students (16 binge-drinkers) via two fMRI sessions at ages 18–19 and 20–21. Using a seed-to-voxel approach, RS-FC differences were examined in nodes of the main brain functional networks vulnerable to alcohol misuse, according to previous studies. Group differences in RS-FC were observed in four of the explored brain regions. Binge drinkers, compared to the control group, exhibited, at the second assessment, decreased connectivity between the right SFG (executive control network) and right precentral gyrus, the ACC (salience network) and right postcentral gyrus, and the left amygdala (emotional network) and medial frontal gyrus/dorsal ACC. Conversely, binge drinkers showed increased connectivity between the right Nacc (reward network) and four clusters comprising bilateral middle frontal gyrus (MFG), right middle cingulate cortex, and right MFG extending to SFG. Maintaining a BD pattern during critical neurodevelopmental years impacts RS-FC, indicating mid-to-long-term alterations in functional brain organization. This study provides new insights into the neurotoxic effects of adolescent alcohol misuse, emphasizing the need for longitudinal studies addressing the lasting consequences on brain functional connectivity.
PB Elsevier
YR 2025
FD 2025
LK https://hdl.handle.net/10347/38820
UL https://hdl.handle.net/10347/38820
LA eng
NO Samuel Suárez-Suárez, Fernando Cadaveira, Alfonso Barrós-Loscertales, José Manuel Pérez-García, Socorro Rodríguez Holguín, Javier Blanco-Ramos, Sonia Doallo, Influence of binge drinking on the resting state functional connectivity of university Students: A follow-up study, Addictive Behaviors Reports, Volume 21, 2025, 100585, ISSN 2352-8532, https://doi.org/10.1016/j.abrep.2025.100585.
NO Ministerio de Ciencia, Innovación y Universidades
NO Xunta de Galicia (GRC ED431C 2021/08)
DS Minerva
RD 28 abr 2026