RT Journal Article
T1 Unexpected Chiro-Thermoresponsive Behavior of Helical Poly(phenylacetylene)s Bearing Elastin-Based Side Chains
A1 Arias, Sandra
A1 Freire Iribarne, Félix Manuel
A1 Calderon, Marcelo
A1 Bergueiro Álvarez, Julián
K1 Chiro-thermoresponsive materials
K1 Helical structures
K1 Self-assembly
K1 Thermoresponsive polymers
AB The thermoresponsive behavior of an elastin-based polymer can be altered by the polymeric macromolecular conformation. Thus, when the elastin basic amino acid sequence VPGVG is used as a pendant group of a poly(phenylacetylene) (PPA) its thermoresponsive behavior in water can be remotely detected through conformational changes on the formed helix. Circular dichroism at different temperatures shows an inversion of the first Cotton effect (450 nm) at 25.8 °C that matches with the cloud point temperature. The elastin-based side-chain poly(phenylacetylene) shows an upper critical solution temperature with low pH and concentration dependency, not expected in elastin-based polymers. It was found that the polymer self-assembles in water into spherical nanoparticles with hydrodynamic diameters of 140 nm at the hydrophobic state.
PB Wiley
YR 2017
FD 2017-08-09
LK http://hdl.handle.net/10347/16402
UL http://hdl.handle.net/10347/16402
LA eng
NO S. Arias, F. Freire, M. Calderón, J. Bergueiro, Angew. Chem. Int. Ed. 2017, 56, 11420
NO Fundación Segundo Gil DávilaDahlem Research School, Freie Universität Berlin. Grant Number: Dahlem International PostDocs fellowshipMinisterio de Ciencia e Innovación. Grant Number: CTQ2015-70519-PXunta de Galicia. Grant Number: Centro Singular de Investigación de Galicia Acreditación 2016-2019European Regional Development Fund. Grant Number: ERDFBundesministerium für Bildung und Forschung. Grant Number: Nanomatfutur award, 13N12561, Thermonanogele
DS Minerva
RD 24 abr 2026