RT Journal Article T1 Relevance of nutritional assessment and treatment to counteract cardiac cachexia and sarcopenia in chronic heart failure A1 Fernández Pombo, Antía A1 Rodríguez Carnero, María Gemma A1 Castro País, Ana Isabel A1 Cantón Blanco, Ana A1 Loures Seoane, María Luisa A1 Casanueva Freijo, Felipe A1 Crujeiras Martínez, Ana Belén A1 Martínez Olmos, Miguel Ángel K1 Cardiac cachexia K1 Sarcopenia K1 Chronic heart failure K1 Muscle wasting K1 Malnutrition AB Chronic heart failure (CHF) is frequently associated with the involuntary loss of body weight and muscle wasting, which can determine the course of the disease and its prognosis. While there is no gold standard malnutrition screening tool for their detection in the CHF population, several bioelectrical and imaging methods have been used to assess body composition in these patients (such as Dual Energy X-Ray Absorptiometry and muscle ultrasound, among other techniques). In addition, numerous nutritional biomarkers have been found to be useful in the determination of the nutritional status. Nutritional considerations include the slow and progressive supply of nutrients, avoiding high volumes, which could ultimately lead to refeeding syndrome and worsen the clinical picture. If oral feeding is insufficient, hypercaloric and hyperproteic supplementation should be considered. β-Hydroxy-β-methylbutyrate and omega-3 polyunsaturated fatty acid administration prove to be beneficial in certain patients with CHF, and several interventional studies with micronutrient supplementation have also described their possible role in these subjects. Taking into account that CHF is sometimes associated with gastrointestinal dysfunction, parenteral nutritional support may be required in selected cases. In addition, potential therapeutic options regarding nutritional state and muscle wasting have also been tested in clinical studies. This review summarises the scientific evidence that demonstrates the necessity to carry out a careful nutritional evaluation and nutritional treatment to prevent or improve cardiac cachexia and sarcopenia in CHF, as well as improve its course PB Elsevier YR 2021 FD 2021-09 LK http://hdl.handle.net/10347/27530 UL http://hdl.handle.net/10347/27530 LA eng NO Clinical Nutrition 40 (2021) 5141-5155 DS Minerva RD 25 abr 2026