RT Journal Article
T1 Anatomy, histochemistry, and imunohistochemistry of the olfactory subsystems in mice
A1 Barrios, Arthur W.
A1 Núñez, Gonzalo
A1 Sánchez Quinteiro, Pablo
A1 Salazar Beloqui, Ignacio
K1 Nasal cavity
K1 Morphology
K1 Digital atlas
K1 Olfactory epithelium
K1 Subdivisions
K1 Mouse
AB The four regions of the murine nasal cavity featuring olfactory neurons were studiedanatomically and by labeling with lectins and relevant antibodies with a view to establishingcriteria for the identification of olfactory subsystems that are readily applicable to othermammals. In the main olfactory epithelium and the septal organ the olfactory sensoryneurons (OSNs) are embedded in quasi-stratified columnar epithelium; vomeronasal OSNsare embedded in epithelium lining the medial interior wall of the vomeronasal duct and donot make contact with the mucosa of the main nasal cavity; and in Grüneberg’s gangliona small isolated population of OSNs lies adjacent to, but not within, the epithelium. Withthe exception of Grüneberg’s ganglion, all the tissues expressing olfactory marker protein(OMP) (the above four nasal territories, the vomeronasal and main olfactory nerves, andthe main and accessory olfactory bulbs) are also labeled by Lycopersicum esculentumagglutinin, while Ulex europaeus agglutinin I labels all and only tissues expressing Gαi2(the apical sensory neurons of the vomeronasal organ, their axons, and their glomerulardestinations in the anterior accessory olfactory bulb). These staining patterns of UEA-I andLEA may facilitate the characterization of olfactory anatomy in other species. A 710-s
PB Frontiers Media
SN 1662-5129
YR 2014
FD 2014
LK http://hdl.handle.net/10347/22224
UL http://hdl.handle.net/10347/22224
LA eng
NO Barrios, A. W., Núñez, G., Sánchez Quinteiro, P., & Salazar, I. (2014). Anatomy, histochemistry, and immunohistochemistry of the olfactory subsystems in mice. Frontiers in neuroanatomy, 8, 63.
NO Private financial support is gratefully acknowledged
DS Minerva
RD 3 may 2026