RT Journal Article
T1 Iterative catalyst controlled diastereodivergent synthesis of polypropionates
A1 Roke, Diedrik
A1 Fañanás-Mastral, Martín
A1 Feringa, Ben L.
AB Polypropionate fragments are synthesized using a combination of a copper-catalyzed asymmetric allylic alkylation, ruthenium-catalyzed cross-metathesis and iridium-catalyzed asymmetric allylic etherification. The use of an appropriate chiral ligand for each catalytic reaction allows access to 1,2-hydroxymethyl arrays with good to excellent control over the relative and absolute configuration of the different stereocenters.
PB Royal Society of Chemistry
YR 2016
FD 2016-11-01
LK http://hdl.handle.net/10347/16978
UL http://hdl.handle.net/10347/16978
LA eng
NO Roke, D., Fañanás-Mastral, M., & Feringa, B. (2016). Iterative catalyst controlled diastereodivergent synthesis of polypropionates. Organic Chemistry Frontiers, 3(11), 1383-1391. doi: 10.1039/c6qo00199h
NO Financial support from The Netherlands Organization forScientific Research (NWO-CW), the National Research Schoolof Catalysis (NRSC-C) and the Ministry of Education, Cultureand Science (Gravitation Program 024.001.035) is gratefullyacknowledged
DS Minerva
RD 28 abr 2026