RT Journal Article
T1 Population genetic and evolution analysis of controversial genus Edwardsiella by multilocus sequence typing
A1 Buján Gómez, Noemí
A1 Balboa Méndez, Sabela
A1 López Romalde, Jesús
A1 Estévez Toranzo, María Alicia Carolina
A1 Magariños Ferro, Beatriz
K1 Pathogen
K1 Edwardsiella
K1 MultiLocus
K1 Evolution
K1 Population
AB At present, the genus Edwardsiella compiles five species: E. tarda, E. hoshinae, E. ictaluri, E. piscicida and E. anguillarum. Some species of this genus such us E. ictaluri and E. piscicida are important pathogens of numerous fish species. With the description of the two latter species, the phylogeny of Edwardsiella became more complicated. With the aim to clarify the relationships among all species in the genus, a multilocus sequence typing (MLST) approach was developed and applied to characterize 56 isolates and 6 reference strains belonging to the five Edwardsiella species. Moreover, several analyses based on the MLST scheme were performed to investigate the evolution within the genus, as well as the influence of recombination and mutation in the speciation. Edwardsiella isolates presented a high genetic variability reflected in the fourteen sequence types (ST) represented by a single isolates out of eighteen total ST. Mutation events were considerably more frequent than recombination, although both approximately equal influenced the genetic diversification. However, the speciation among species occurred mostly by recombination. Edwardsiella genus displays a non-clonal population structure with some degree of geographical isolation followed by a population expansion of E. piscicida. A database from this study was created and hosted on pubmlst.org (http://pubmlst.org/edwardsiella/).
PB Elsevier
YR 2018
FD 2018
LK https://hdl.handle.net/10347/39042
UL https://hdl.handle.net/10347/39042
LA eng
NO Molecular Phylogenetics and Evolution Volume 127, October 2018, Pages 513-521
NO The work was supported by Ministerio de Economía y Competitividad (Spain) 426 [AGL2012-31049, BES-2010-037413] and Xunta de Galicia (Spain) [GRC-2014/007].
DS Minerva
RD 28 abr 2026