RT Journal Article
T1 Osmolality and pH of commercially available contact lens care solutions and eye drops
A1 Pena Verdeal, Hugo
A1 García Queiruga, Jacobo
A1 García Resúa, Carlos
A1 Yebra-Pimentel Vilar, Eva
A1 Giráldez Fernández, María Jesús
K1 Eye drops
K1 Lens care solutions
K1 Osmolality
K1 Ph
K1 Viscosity/lubrication-enhancing principles
AB Purpose: The physical properties of contact lens care solutions and Eye Drops (ED) may affect initial comfort and dry eye symptomatology in contact lens wearers, although these properties are not always provided by manufacturers. The present study aimed to measure and compare the osmolality and pH of commercially available contact lens care solutions and ED.Methods: Forty-four solutions were tested (17 lens care solutions and 27 ED) and classified by the presence and/or combination of the viscosity/lubrication-enhancing ingredients. Solution osmolality was obtained with the Fiske 110 osmometer and pH was measured with a micro-pH 2000. Each measurement was taken ten times, following the manufacturer's instructions, while controlling for room temperature and humidity. Differences between the values of the physical properties of the solutions were analysed by type and viscosity/lubrication-enhancing agent subclassification.Results: Osmolality ranged from 192.6 ± 2.17 to 364.6 ± 2.88 mOsm/Kg, while pH ranged from 6.35 [6.35-6.26] to 7.99 [7.99-8.00]. A significant difference in the osmolality and pH values of contact lens care solutions and ED was found when classified by type or viscosity/lubrication-enhancing agent (ANOVA and Kruskal-Wallis respectively, both p < 0.001).Conclusions: The physical properties of some contact lens care solutions and ED are not readily available. The osmolality and pH values of various commercially available lens care solutions and ED vary significantly both by type and viscosity/lubrication-enhancing ingredients.
PB Elsevier
SN 1367-0484
YR 2021
FD 2021-08
LK http://hdl.handle.net/10347/32140
UL http://hdl.handle.net/10347/32140
LA eng
NO Hugo Pena-Verdeal, Jacobo Garcia-Queiruga, Carlos García-Resúa, Eva Yebra-Pimentel, María J. Giráldez, Osmolality and pH of commercially available contact lens care solutions and eye drops, Contact Lens and Anterior Eye, Volume 44, Issue 4, 2021, 101379, ISSN 1367-0484, https://doi.org/10.1016/j.clae.2020.10.009.
DS Minerva
RD 23 abr 2026