RT Dissertation/Thesis
T1 Forensic Ancestry Analysis with Autosomal Polymorphisms
A1 Phillips, Christopher Paul
K1 Inferencia de Ancestralidad / Ancestry inference
K1 Análisis forense de ADN / Forensic DNA analysis
K1 Genética de poblaciones / Population genetics
K1 Polimorfismo nucleótido único/Single nucleotide polymorphism
AB The inference of ancestry from biological material left at a crimescene has been a longstanding but specialised forensic technique, often lacking sufficient detail to make a reliable inference of ancestr y. This thesis describes the key steps in developing a forensic ancestry test that can be adopted byany laboratory using capillary electrophoresis equipment: optimisation of a PCR multiplex to detectDNA markers from contact traces; compilation of population data from which to infer the likely pop ulation of origin of the person; detection of coancestry patterns in an individual with admixed backgr ounds; and development of online statistical tools that calculate the probability of an individual’s an cestry from a submitted SNP profile. Additional types of autosomal markers were compiled from Ind el polymorphisms; short tandem repeats (STRs); multiple allele SNPs; and Microhaplotype markers.
YR 2017
FD 2017
LK http://hdl.handle.net/10347/16134
UL http://hdl.handle.net/10347/16134
LA eng
DS Minerva
RD 29 abr 2026