RT Dissertation/Thesis T1 Engineering smart nano metal-organic frameworks for biomedical applications A1 CedrĂșn Morales, Manuela K1 MOFs K1 nanoparticles K1 drug delivery K1 nanomedicine AB This thesis aims to advance nanomedicine by developing nanometal-organic frameworks for enhanced drug delivery. Varioussystems were synthesized and tailored to investigate theirencapsulation abilities and surface modi ications to providethem with targeting capabilities. Additionally, nanocompositesresponsive to near-infrared (NIR) light were created,comprising a core of gold nanoparticles and a shell of nanometal-organic frameworks. These intelligent nanocarrierswere designed to facilitate intracellular cargo delivery throughinnovative strategies. YR 2024 FD 2024 LK http://hdl.handle.net/10347/34506 UL http://hdl.handle.net/10347/34506 LA eng DS Minerva RD 27 abr 2026