RT Book,_Section
T1 Design and Synthesis of Crown Ether Thiosemicarbazones
A1 Lucio Martínez, Fátima
A1 Munín Cruz, Paula
A1 Reigosa Chamorro, Francisco
A1 Fernández Figueiras, Adolfo
A1 Polo Ces, Paula María
A1 Pereira Lorenzo, María Teresa
A1 Vila Abad, José Manuel
K1 DFT
K1 Crown Ethers
K1 Thiosemicarbazones
AB Thiosemicarbazones are well known compounds that show antitumoral and antibacterial proprieties[1] ; while crown ether moiety acts as ion sensor to entrap cations size-selectively from the environment, implied in the production of sensors, membrane ion transport or potential anti-cancerous species, among others[2]. The combination of both functions into the same molecule should increase their unique applications.Herein we report on the synthesis of a molecule that combines both functions. The main aspect is that the study has being performed beginning with the design of the compound using DFT calculations, with the package of programs g09[3], after which follows the final synthesis and characterization using 1H NMR, IR and crystallographic analysis
PB MDPI
SN 978-3-03842-192-4
YR 2016
FD 2016
LK http://hdl.handle.net/10347/25747
UL http://hdl.handle.net/10347/25747
LA eng
NO Lucio-Martínez, F., Munín, P., Reigosa, F., Fernández-Figueiras, A., Polo-Ces, P., Pereira, M.T. &  Vila, J.M. (2016). Design and Synthesis of Crown Ether Thiosemicarbazones. In J.A. Seijas, M.P. Vázquez Tato & S.K. Lin. (Ed.), Proceedings ECSOC-20: The 20Th International Electronic Conference On Synthetic Organic Chemistry: November 1-30, 2016. MDPI. doi: 10.3390/ecsoc-20-e013
NO The 20th International Electronic Conference on Synthetic Organic Chemistry session Computational Chemistry
NO We wish to thank the financial support received from the Xunta de Galica (Galicia, Spain) under the Grupos de Referencia Competitiva Programme Projects GRC2015/009. F.Lucio thanks the Spanish Ministry of Education (grant FPU13/05014)
DS Minerva
RD 3 may 2026