RT Journal Article
T1 Membrane-disrupting iridium(III) oligocationic organometallopeptides
A1 Salvadó, Iria
A1 Gamba, Ilaria
A1 Montenegro García, Javier
A1 Martínez Costas, José Manuel
A1 Brea Floriani, José Manuel
A1 Loza García, María Isabel
A1 Vázquez López, Miguel
A1 Vázquez Sentís, Marco Eugenio
AB A series of oligoarginine peptide derivatives containing cyclometallated iridium(III) units display remarkable cytotoxicity, comparable to that of cisplatin. In vitro studies with unilamellar vesicles support a membrane-disrupting mechanism of action
PB Royal Society of Chemistry
SN 1359-7345
YR 2016
FD 2016-08-19
LK http://hdl.handle.net/10347/15772
UL http://hdl.handle.net/10347/15772
LA eng
NO Salvadó, I, Gamba, I, Montenegro J, Martínez-Costas J, Brea JM, Loza MI, Vázquez López M, Vázquez M.E. Membrane-disrupting iridium(III) oligocationic organometallopeptides. Chem. Commun., 2016,52, 11008-11011. DOI: 10.1039/C6CC05537K
NO NOTICE:  This is the peer reviewed version of the following article: Salvadó, I, Gamba, I, Montenegro J, Martínez-Costas J, Brea JM, Loza MI, Vázquez López M, Vázquez M.E. Membrane-disrupting iridium(III) oligocationic organometallopeptides. Chem. Commun., 2016,52, 11008-11011. DOI: 10.1039/C6CC05537K.  This article may be used for non-commercial purposes in accordance with RSC Terms and Conditions for self-archiving
NO We are thankful for the support given by the Spanish grants SAF2013-41943-R, CTQ2015-70698-R, CTQ2013-49317-EXP,CTQ2014-59646-R, and BFU2013-43513-R, and the Xunta de Galicia GRC2013-041. Support from COST Action CM1105 and the orfeo-cinqa network (CTQ2014-51912-REDC) is kindly acknowledged
DS Minerva
RD 28 abr 2026