RT Dissertation/Thesis
T1 New Catalytic Routes to Benzofused Seven-Membered Azaheterocycles
A1 Velasco Rubio, Álvaro
K1 Catalysis
K1 Benzazepines
K1 Benzodiazepines
K1 Benzoxazepines
AB Benzazepines, benzodiazepines and benzoxazepines compose a privilegedfamily of natural products and pharmaceuticals. Their remarkable biological activity made them useful drugs to treata large variety of issues. The design of new catalytic sustainable routes to these nuclei still remains as a mainchallenge to the organic chemistry. In this thesis the synthesis of these three nuclei upon generation of a key metalp-allyl intermediate through Csp2-H activation, allylic C-H activation, and Rh-hydride catalysis have beensuccessfully accomplished.
YR 2021
FD 2021
LK http://hdl.handle.net/10347/27488
UL http://hdl.handle.net/10347/27488
LA eng
DS Minerva
RD 24 abr 2026