RT Journal Article
T1 First nation-wide estimation of tobacco consumption in Spain using wastewater-based epidemiology
A1 Montes Goyanes, Rosa
A1 Rodil Rodríguez, María del Rosario
A1 Rico, Andreu
A1 Cela Torrijos, Rafael
A1 González Mariño, Iria
A1 Hernández, Félix
A1 Bijlsma, Lubertus
A1 Celma, Alberto
A1 Picó, Yolanda
A1 Andreu, Vicente
A1 López de Alda, Miren
A1 López-García, Ester
A1 Postigo, Cristina
A1 Pocurull, Eva
A1 Marcé, Rosa María
A1 Rosende, María
A1 Olivares, Maitane
A1 Valcárcel, Yolanda
A1 Quintana Álvarez, José Benito
K1 Nicotine
K1 Nation wide monitoring
K1 Sewage surveillance
K1 Addiction
AB Wastewater-based epidemiology (WBE) has become a very useful tool to monitor a population's drug consumption or exposure to environmental and food contaminants. In this work, WBE has been applied to estimate tobacco consumption in seven Spanish regions. To this end, 24 h composite wastewater samples were taken daily for one week in 17 wastewater treatment plants, covering altogether a population of ca. 6 million inhabitants. The samples were treated by enzymatic deconjugation and the wastewater content of two human-specific nicotine metabolites (namely, cotinine and trans-3′-hydroxycotinine) was measured to estimate the daily consumption of nicotine. The population-weighted average nicotine consumption in the seven analyzed regions was 2.2 g/(day∙1000 inh.), without any daily pattern. This average estimated nicotine consumption value agreed with the value derived from official tobacco sales data. Differences in consumption among the seven studied regions were found, being Galicia, the region with the lowest rate, and the Basque Country and Catalonia those with the highest rates. However, no conclusive correlation was found between those values and the prevalence data taken from two different national surveys, nor sociodemographic and health data. This study demonstrates that this tool can complement other indicators in order to accurately assess tobacco consumption rates at regional and national levels and provides the most extensive application of the approach in the Spanish territory.
PB Elsevier
SN 0048-9697
YR 2020
FD 2020
LK http://hdl.handle.net/10347/26047
UL http://hdl.handle.net/10347/26047
LA eng
NO Science of the Total Environment, 741 (2020), 140384. https://doi.org/10.1016/j.scitotenv.2020.140384
NO This study was supported by MINECO/AEI projects (CTM2016-81935-REDT, CTM2017-84763-C3-2-R, CTM2017-84763-C3-1-R, CTM2017-84763-C3-3-R), MICINN project (CEX2018-000794-S), Galician Council of Culture, Education and Universities (ED481D 2017/003 and ED431C2017/36), cofunded by FEDER/ERDF
DS Minerva
RD 27 abr 2026