RT Journal Article T1 Caproic acid production is linked to biomass activity during xylose fermentation A1 Iglesias Riobó, Juan A1 Mauricio Iglesias, Miguel A1 Carballa Arcos, Marta K1 CSTR K1 Hydraulic retention time K1 Organic loading rate K1 SBR K1 Solid retention time AB This study aims at addressing inconsistencies in literature regarding the organic loading rate (OLR) and hydraulic retention time (HRT) effect on caproic acid production, using biomass activity as an indicator. Xylose was fully consumed in the reference CSTR and SBR (HRT = 1-day; OLR = 12 g COD/(L·d)), but different caproic acid yields (0.02 vs 0.11 Cmol/Cmol-s) were observed, which was linked to differences in biomass activity (12 vs 3.5 g/(g VSS·d)). At HRT 0.5 days, xylose conversion was incomplete and lactic acid and ethanol appeared, reducing caproic acid production. However, increasing xylose concentration in the feeding to 24 g COD/L did not change the caproic acid yield (0.12 Cmol/Cmol-s), which was explained by similar biomass activity as in the reference SBR (4.8 g/(g VSS·d)). These findings indicate that the SBR is the optimal configuration, since it allows maintaining a low biomass activity and therefore a high caproic acid yield. PB Elsevier YR 2025 FD 2025-02 LK https://hdl.handle.net/10347/38164 UL https://hdl.handle.net/10347/38164 LA eng NO Bioresource Technology Volume 418, February 2025, 131952 NO This research was framed in CELL4CHEM project (PCI2021-121989, ERACoBioTech 3rd call) funded by MICIU/AEI/10.13039/501100011033 and the European Union NextGenerationEU/PRTR. The authors belong to a Galician Competitive Research Group (ED431C-2021/37) DS Minerva RD 22 abr 2026