RT Journal Article
T1 Magnetic resonance imaging for the study of mediastinal adenopathies in lung cancer: Comparison with standard tests
A1 Pereiro Brea, Tara
A1 Martínez de Alegría, Anxo
A1 Valdés Cuadrado, Luis
A1 Golpe Gómez, Antonio
A1 Carreira Villamor, José Martin
A1 Ruano Raviña, Alberto
K1 Adenopathies
K1 Computed tomography
K1 Lung cancer
K1 Magnetic resonance
K1 Positron-emission tomography
K1 Staging
AB Background: Lung cancer is the second most common cancer in both men and women. Mediastinal lymph node involvement in these patients, determined by imaging tests, indicates prognosis and modifies therapeutic attitude.Purpose: The aim of this study was to analyze the diagnostic capacity of magnetic resonance imaging (MRI) in the study of the mediastinum in comparison with conventional tests (computed tomography [CT] and positron-emission tomography [PET] or PET/CT scans), taking histology as the gold standard.Materials and Methods: An observational study was conducted on 16 patients with suspicion of primary lung cancer (June 2016 through December 2018). We studied their demographic characteristics and used CT, PET, or PET/CT scans and MRI (diffusion-weighted imaging-MRI sequence) to examine mediastinal disease and compare MRIs diagnostic yield and percentage agreement to that of conventional tests.Results: As compared to CT and PET scanning, MRI displayed a very low sensitivity and a specificity of 90 and 88%, respectively; positive predictive value was 0.67 (both) and negative predictive value (NPV) was 0.28 and 0.22, respectively. MRI showed a high degree of agreement in lymph node diagnosis when compared with histology (91.2%; P = 0.001): specificity in this case was high (E = 0.94), as was the NPV (NPV = 0.97).Conclusions: The results of this study would appear to indicate that MRI could play a relevant role in mediastinal staging of lung cancer. More prospective, multicenter studies are, however, needed to be able to draw up firm recommendations about the role of MRI and its place in lung cancer staging
PB Wolters Kluwer
SN 0973-1482
YR 2021
FD 2021-09-14
LK https://hdl.handle.net/10347/40450
UL https://hdl.handle.net/10347/40450
LA eng
NO Pereiro-Brea, Tara1,; de Alegría, Anxo Martínez2; Valdés, Luis3,4; Golpe-Gómez, Antonio3; Carreira-Villamor, José Martín2; Ruano-Raviña, Alberto PhD5,6. Magnetic resonance imaging for the study of mediastinal adenopathies in lung cancer: Comparison with standard tests. Journal of Cancer Research and Therapeutics 17(4):p 917-924, Jul–Sep 2021. | DOI: 10.4103/jcrt.JCRT_1626_20
DS Minerva
RD 26 abr 2026